Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.ajog.2016.08.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Antioxidant treatment attenuates age-related placenta GLUT-1 and PLIN-2 downregulation.
Placenta
December 2024
Ageing and Stress Group, i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Rua Alfredo Allen, 208, 4200-135, Porto, Portugal; Faculdade de Medicina Veterinária da Universidade Lusófona e Instituto Politécnico da Lusofonia, COFAC - Cooperativa de Formação e Animação Cultural, C.R.L., Campo Grande 376, 1749-024, Lisboa, Portugal; Escola Superior de Saúde, Politécnico do Porto, Rua Dr. António Bernardino de Almeida 400, 4200-072, Porto, Portugal. Electronic address:
Background And Aim: Pregnancy after the age of 35 is correlated with an increased risk of impaired placentation and the development of pregnancy-associated complications. Changes in uterine redox balance seem to play a role in these settings. In this work, we hypothesized that local redox dysregulation impacts the placenta metabolic profile.
View Article and Find Full Text PDFEditorial: Benefits and risks of agonist triggering strategies.
Front Endocrinol (Lausanne)
December 2024
MARGen Clinic, Granada, Spain.
Elevated levels of exogenous prolactin promote inflammation at the maternal-fetal interface via the JAK2/STAT5B signaling axis.
Front Immunol
January 2025
Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, GA, United States.
The placenta is a unique organ with various immunological and endocrinological roles that modulate maternal and fetal physiology to promote maternal-fetal tolerance, pregnancy maintenance, and parturition at term. During pregnancy, the hormone prolactin (PRL) is constitutively secreted by the placenta and is necessary for implantation, progesterone support, fetal development, and overall immune modulation. While PRL is essential for pregnancy, studies suggest that elevated levels of serum PRL (hyperprolactinemia) are associated with adverse pregnancy outcomes, including miscarriage, preterm birth, and preeclampsia.
View Article and Find Full Text PDFEstablishing a Swine Model to Study Uterus Dynamic Preservation and Transplantation.
J Vis Exp
December 2024
Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Harvard Medical School; Shriners Children's Boston;
Article Synopsis
- Uterus transplantation is currently the only solution for women with absolute uterine infertility, such as those with Rokitansky syndrome, allowing them to experience pregnancy and childbirth.
- There are significant challenges with uterus transplantation, including the risks of ischemia-reperfusion injury and a notable thrombotic complication rate of up to 20%, which can lead to graft rejection.
- This protocol aims to outline the surgical steps for obtaining porcine uteruses and implementing dynamic preservation through machine perfusion, which may reduce hypoxic injury compared to traditional static cold storage methods.
Linguistic Validation of a British-English Version of the SAMANTA Questionnaire and HMB-VAS Tool: A Step Toward Improved Diagnosis of Heavy Menstrual Bleeding.
Womens Health Rep (New Rochelle)
December 2024
Hospital de Sant Pau, Barcelona, Spain.
Background: Heavy menstrual bleeding (HMB) is a common disorder interfering with physical, emotional and social domains, and overall quality of life (QoL). The Heavy Menstrual Bleeding-Visual Analog Scale (HMB-VAS) tool, including the VAS for menstrual bleeding intensity (VAS-Int) and the VAS for its interference with daily activities (VAS-Imp), is useful for HMB screening. The SAMANTA questionnaire (SAMANTA-Q) was developed and psychometrically validated in Spanish to easily identify women with HMB.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!