Using the method of mathematical planning of experiment the effect of calcium, magnesium, manganese, iron, zinc and copper on synthesis of antibiotic and pigment by mycophilic fungus Hypomyces rosellus has been studied. The ions of Mg2+, Mn2+, Fe2+ have been found to be important for antibiotic and pigment formation by fungus, the ions of Mg2+ and Mn2+ are interchangeable.
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