[Dermatomyositis and Panniculitis: the function of immunoglobulins].

Pan Afr Med J

Service de Médecine Interne Hôpital Militaire de Tunis, Montfleury, Tunisie.

Published: February 2017

AI Article Synopsis

  • - Panniculitis is an inflammatory condition affecting the fatty tissue beneath the skin and is rarely linked to dermatomyositis, potentially appearing before, after, or at the same time as muscle damage.
  • - In most cases, panniculitis and dermatomyositis respond positively to treatments with corticosteroids and immunosuppressants.
  • - A case study of a 48-year-old patient shows that after developing panniculitis lesions two months prior to muscle symptoms, traditional treatments were ineffective; however, using polyvalent immunoglobulin improved both skin and muscle issues.

Article Abstract

Panniculitis is an inflammatory disease of subcutaneous adipose tissue which is rarely associated with dermatomyositis. It can occur before, after or simultaneously with muscle damage. In most cases, the evolution of panniculitis and of other dermatomyositis affections is favorable with corticosteroids and/or immunosuppressants. We report the case of a 48 year-old patient who developed panniculitis lesions 2 months before having muscular signs. Skin involvement was resistant to corticosteroid treatment associated with immunosuppressants drugs. This led to the use of polyvalent immunoglobulin treatment improving both skin and muscle damage.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963182PMC
http://dx.doi.org/10.11604/pamj.2016.23.262.6213DOI Listing

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