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http://dx.doi.org/10.1534/genetics.116.193003 | DOI Listing |
J Neurogenet
July 2021
Department of Genetics and Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA.
Sexual dimorphism is a device that supports genetic diversity while providing selective pressure against speciation. This phenomenon is at the core of sexually reproducing organisms. provides a unique experimental system where males exist in a primarily hermaphroditic species.
View Article and Find Full Text PDFGenetics
August 2016
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853
Biochem Biophys Res Commun
October 2011
MRC Toxicology Unit, Leicester, UK.
Programmed cell death was a fundamental discovery, awarded with the Nobel price in 2002 to Sulston, Brenner and Horvitz. Since then it has been clear that alteration of apoptotic pathways is a common feature of tumors, enabling cancer cells to survive chemotherapeutic interventions. Thus, apoptosis is an attractive target in cancer therapy, with the aim to revert the cancer-related alterations of the cell death machinery.
View Article and Find Full Text PDFAging Cell
August 2011
Buck Institute for Age Research, 8001 Redwood Blvd., Novato, CA 94945, USA.
The roundworm C. elegans is widely used as an aging model, with hundreds of genes identified that modulate aging (Kaeberlein et al., 2002.
View Article and Find Full Text PDFComp Funct Genomics
June 2010
MRC UK HGMP-RC, Hinxton, Cambridge CB10 1SB, UK.
We bring you the highlights of the second Joint Cold Spring Harbor Laboratory and Wellcome Trust 'Genome Informatics' Conference, organized by Ewan Birney, Suzanna Lewis and Lincoln Stein. There were sessions on in silico data discovery, comparative genomics, annotation pipelines, functional genomics and integrative biology. The conference included a keynote address by Sydney Brenner, who was awarded the 2002 Nobel Prize in Physiology or Medicine (jointly with John Sulston and H.
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