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Amyloidosis as a Renal Complication of Chronic Granulomatous Disease. | LitMetric

AI Article Synopsis

  • Chronic granulomatous disease is a rare genetic immune disorder that makes individuals more prone to infections and severe inflammation.
  • There have been documented genitourinary issues associated with this disease, such as hydronephrosis and granulomatous cystitis, but amyloidosis is a rare complication.
  • This report highlights a case of a patient with chronic granulomatous disease who developed amyloidosis later in their illness.

Article Abstract

Chronic granulomatous disease is a rare primary immunodeficiency disorder, which leads to increased susceptibility to recurrent infections and severe inflammatory manifestations.  There have been reports regarding different aspects of genitourinary involvement in chronic granulomatous disease, some of which are hydronephrosis, granulomatous cystitis, and glomerulonephritis, but among these complications, amyloidosis is rather rare. We report a patient with chronic granulomatous disease that developed amyloidosis later in the course of the disease.

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