AI Article Synopsis
- The development of drugs for treating psychosis reveals important insights into mental and movement disorders.
- The acceptance of less potent dopamine antagonists has decreased the risk of drug-induced movement disorders, but increased marketing and off-label use have raised concerns about more people being affected.
- Familiarity with recent advancements in diagnosis and management can improve patient safety and treatment effectiveness while shedding light on how antipsychotic drugs work in the brain.
Article Abstract
The development of drugs to treat psychosis is a fascinating nexus for understanding mechanisms underlying disorders of mind and movement. Although the risk of drug-induced extrapyramidal syndromes has been mitigated by the acceptance of less potent dopamine antagonists, expansive marketing and off-label use has increased the number of susceptible people who may be at risk for these neurologic effects. Clinicians need to be familiar with advances in diagnosis and management, which are reviewed herein. A better understanding of drug-induced effects on the motor circuit may improve patient safety, enhance antipsychotic effectiveness, and provide insights into mechanisms underlying antipsychotic activity in parallel brain circuits.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.psc.2016.04.003 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!