When Mr. Fap Meets the Gals.

Cell Host Microbe

Biological Sciences, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address:

Published: August 2016

Fusobacteria are found to be overrepresented in the colorectal tumor microenvironment. In this issue of Cell Host & Microbe, Abed et al. (2016) describe a novel homing mechanism by which fusobacteria localize to tumors by recognizing a host polysaccharide (Gal-GalNAc) on cancer cells using a fusobacterial lectin, Fap2.

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Source
http://dx.doi.org/10.1016/j.chom.2016.07.013DOI Listing

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