AI Article Synopsis
- The study looked at how well a test called repetitive nerve stimulation (RNS) works to diagnose a condition called myasthenia gravis (MG) by examining different muscles.
- They found that testing 12 muscles on both sides of the body had a global success rate of 82%, meaning it correctly identified the condition most of the time.
- The best muscles to check for accurate results were identified as the anconeus, orbicularis oculi, and trapezius, so doctors should test these muscles for better diagnosis.
Article Abstract
Introduction: The diagnostic sensitivity of repetitive nerve stimulation (RNS) in patients with myasthenia gravis (MG) varies as a function of the number of muscles or the choice of muscles studied.
Methods: By exploring 12 muscles bilaterally, we evaluated the global sensitivity of RNS at rest, the sensitivity in different clinical forms, and the sensitivity of different combinations of muscles studied.
Results: The global sensitivity of RNS was 82%, and specificity was 100%. The sensitivity in the MG subgroups was as follows: ocular (O) = 67%; oculobulbar (OB) = 86%; and generalized (G) = 89%. The most sensitive muscles were the anconeus in group O, orbicularis oculi (OO) or nasalis in group OB, and the trapezius in group G. Maximum sensitivity was obtained by exploring OO, trapezius, and anconeus bilaterally.
Conclusions: We recommend bilateral exploration of at least 3 muscles, a facial muscle, trapezius, and anconeus. Muscle Nerve 55: 532-538, 2017.
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| http://dx.doi.org/10.1002/mus.25374 | DOI Listing |
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