AI Article Synopsis
- Papillary cystadenocarcinoma (PCAC) is a rare tumor of the salivary glands that mainly grows in cystic forms and presents diagnostic challenges due to its similarities with other cystic papillary tumors.
- A case of PCAC in a 55-year-old male was identified through fine needle aspiration cytology, showing mild atypical features, but further examination revealed more aggressive characteristics.
- The report highlights both the cytological and histological features of PCAC, emphasizing the need for awareness of its potential for metastasis despite its classification as a low-grade malignant tumor.
Article Abstract
Papillary cystadenocarcinoma (PCAC) is a rare salivary gland tumor characterized by a predominantly cystic growth that often exhibits intraluminal papillary growth without specific histologic features of other cystic salivary gland tumors. The preoperative cytological diagnosis can pose a diagnostic challenge as it has to be differentiated from other cystic papillary tumors such as mucoepidermoid carcinoma, papillary cystic variant of acinic cell carcinoma, and low-grade cribriform CAC. It is considered to be a low-grade malignant salivary gland tumor with an indolent biological behavior. We report a case of PCAC of the parotid in a 55-year-old male diagnosed on fine needle aspiration cytology. Although it showed mild atypia cytologically, on excision tumor showed vascular and perineural invasion with regional node metastasis indicating a wider morphologic spectrum than what is described. This prompted us to write a case report describing the cytological and histological features of this rare tumor and also discuss the diagnostic challenges.
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| http://dx.doi.org/10.4103/0377-4929.188114 | DOI Listing |
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