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Inhibition Mechanism of Chitooligosaccharide-Polyphenol Conjugates toward Polyphenoloxidase from Shrimp Cephalothorax.
Molecules
July 2023
International Center of Excellence in Seafood Science and Innovation, Faculty of Agro-Industry, Prince of Songkla University, Hat Yai 90110, Thailand.
Crustaceans are perishable with a short shelf-life. They are prone to deterioration after capture, particularly during handling, processing, and storage due to melanosis caused by polyphenoloxidase (PPO). Therefore, inhibitory effects of chitooligosaccharide (CHOS) in comparison with CHOS-catechin (CHOS-CAT), CHOS-epigallocatechin gallate (CHOS-EGCG), and CHOS-gallic acid (CHOS-GAL) conjugates on Pacific white shrimp cephalothorax PPO were studied.
View Article and Find Full Text PDF[Melanosis of the bladder-a rare diagnosis].
Urologie
November 2023
Klinik für Urologie, Kantonsspital St. Gallen, Rorschacher Str. 95, 9007, St. Gallen, Schweiz.
Melanosis of the urinary bladder is an extremely rare benign condition in which melanin deposits occur in the urothelial and stromal cells. We report such a case in which melanosis of the urinary bladder was detected in a 55-year-old woman with known multiple sclerosis during an extended workup due to urinary urgency complaints. The findings were confirmed by biopsy.
View Article and Find Full Text PDFCurrent Practice in the Treatment of Epithelial and Melanocytic Tumours with Interferon-α2b: A Survey of Tertiary Eye Centres in Germany.
Klin Monbl Augenheilkd
July 2023
Eye Center, University Medical Center Freiburg, Germany.
Purpose: To evaluate the standard of care, in particular the use of topical or subconjunctival interferon-2b, in treating ocular surface squamous neoplasia or melanocytic tumours in tertiary eye centres in Germany.
Methods: A survey containing 14 questions was sent to 43 tertiary eye centres in Germany. The questions addressed the surgical and medical management of ocular surface squamous neoplasia and melanocytic tumours (primary acquired melanosis and malignant melanoma), as well as the clinical experiences and difficulties in prescribing off-label interferon-2b eye drops and subconjunctival injections.
[Laugier-Hunziker syndrome : A rare differential diagnosis of mucocutaneous hyperpigmentation].
Hautarzt
April 2022
Klinik für Dermatologie, Venerologie und Allergologie, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland.
Laugier-Hunziker syndrome (LHS) is characterized by lentiginous hyperpigmentation of the oral mucosa and lips. In addition, longitudinal melanonychia and palmoplantar hyperpigmented lesions may occur. LHS is a clinical diagnosis of exclusion.
View Article and Find Full Text PDF[Hyperplasia-associated cutaneous paraneoplasia].
Hautarzt
April 2021
Klinik für Dermatologie und Allergologie, Hautklinik, Universitätsklinikum Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.
Article Synopsis
- Hyperplasia-associated cutaneous paraneoplasia is a key condition to consider for early diagnosis of underlying tumors, significantly enhancing patient outcomes.
- Hyperplasia is mainly caused by cytokines from primary tumors or metastases, stimulating excessive growth of skin cells (keratinocytes) through growth factors.
- Conditions like Acanthosis Nigricans Maligna and Acrokeratosis Bazex present specific skin changes associated with certain cancers, and treating the primary tumor often helps alleviate skin symptoms but requires monitoring for recurrence.
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