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Rectal Adenocarcinoma With Pagetoid Spread: A Novel Entity.
Case Rep Gastrointest Med
October 2024
Colorectal Surgery, St. Joseph's University Medical Center, Paterson, New Jersey, USA.
Perianal Paget's disease (PPD) is a rare skin adenocarcinoma that arises in the apocrine glands of the perianal region. It is often misdiagnosed as eczema, leukoplakia, squamous cell carcinoma, Bowen's disease, lichen planus, or condylomata acuminata. We report a case of a 63-year-old male who presented to the emergency room (ER) for evaluation of an anal mass that had persisted over 6 months.
View Article and Find Full Text PDFConcurrent Bowen's Disease and Pagetoid Bowen's Disease on the Nipple-Areola Complex: A Case Report and Dermoscopic Findings.
Indian J Dermatol
January 2023
From the Department of Dermatology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
CK 8∕18: the key to differentiating intracutaneous lesions with pagetoid features.
Rom J Morphol Embryol
March 2022
Department of Pathophysiology, George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureş, Romania;
Introduction: Neoplasms with pagetoid features are a category of rare lesions defined by the presence of atypical cells at different levels of the epidermis. The most important diseases within this category are mammary Paget disease (MPD), extramammary Paget disease (EMPD), Bowen's disease, in situ melanoma, and pagetoid reticulosis.
Aim: The aim of this analysis was to describe the importance of the cytokeratin 8∕18 (CK 8∕18) immunostaining in diagnosing MPD and EMPD and differentiating them from other lesions.
Keratin 7 and ERBB2 Negative Mammary Paget Disease Without an Underlying in Situ and Invasive Carcinoma.
Int J Surg Pathol
August 2022
5506Medical College of Wisconsin, 9200 W. Wisconsin Avenue, Milwaukee, WI, USA, 53226-0509.
We report a unique case of a post-menopausal female who presented with a lesion on the areola. A biopsy of the lesion demonstrated a pagetoid intraepithelial neoplasm suggesting a differential diagnosis of mammary Paget disease and pagetoid Bowen disease. Excision of the lesion confirmed the diagnosis of mammary Paget disease with typical histological appearance.
View Article and Find Full Text PDFFocal CK7 Positivity in Pagetoid Bowen's Disease: A Mimic of Extramammary Paget's Disease.
Ann Dermatol
October 2021
Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea.
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