Introduction: Undescended testis or cryptorchidism is detected in 3% of full-term male newborns, and inup to 33% of preemies. As the testicular descent may sometimes resolve spontaneously during first months of life, cryptorchidism is found in 1% of boys one year old. According to Consensus of Nordic experts in. pediatric urology regarding cryptorchidism the optimal period for surgery is 12-18 months of age. The goal of this study was to identify the age of patients with congenital undescended testis at the time of surgery.
Material And Methods: A retrospective study included all the cases of cryptorchid patients who had undergone orchidopexy in the period from 2007 to 2014. The patients'. age and the place of residence were analyzed.
Results: A total of 637 patients (722 orchidopexies) underwent the elective operative treatment of undescended testis during the observed period. The analysis revealed that only 144 (22.60%) of cryptorchid infants were operated on within their first 18 months of life. In the group of 359 patients from* the urban environment, 101 (28.13%) were operated under the age of 18 months. Among the 278 patients from the rural enviornment, 43 (15.46%) were 18 months and younger at the time of surgery.
Conclusion: The timing of surgical treatment of undescended testis in the study period was far from the recommended optimal time. It is evidently necessary to plan and provide additional information for pediatricians and parents about the current view on cryptorchidism and consequences of the late treatment.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.2298/mpns1604106d | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
[Clinical and genetic characteristics analysis of two children with comorbidity of two rare genetic diseases].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
October 2025
Department of Pediatric Neurology, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.
Objective: To explore the clinical and genetic characteristics of two children diagnosed with two rare genetic diseases simultaneously.
Methods: Two children with comorbidity of two genetic diseases due to dual genetic mutations diagnosed at the Third Affiliated Hospital of Zhengzhou University respectively in May 2022 and March 2023 were selected as the study subjects. Clinical and genetic data of the two children were retrospectively analyzed.
LncRNA-MSTRG.19083.1 Targets NTRK2 as a miR-429-y Sponge to Regulate Circadian Rhythm via the cAMP Pathway in Yak Testis and Cryptorchidism.
Int J Mol Sci
December 2024
College of Veterinary Medicine, Gansu Agriculture University, Lanzhou 730070, China.
Long noncoding RNAs (LncRNAs) play essential roles in numerous biological processes in mammals, such as reproductive physiology and endocrinology. Cryptorchidism is a common male reproductive disease. Circadian rhythms are actively expressed in the reproductive system.
View Article and Find Full Text PDFSpigelian hernia and cryptorchidism syndrome: open spigelian hernia repair and laparoscopic one-stage orchiopexy for ectopic testis.
BMJ Case Rep
January 2025
Pediatric Surgical Services, Mary Bridge Children's Hospital and Health Center, Tacoma, Washington, USA
Spigelian hernia and cryptorchidism syndrome in children is increasingly reported in the literature. A variety of phenotypes have been reported, so diagnostic approaches and operative techniques remain poorly defined. The case of an infant male who presented with a left spigelian hernia and ipsilateral cryptorchidism who was initially misdiagnosed with an ectopic inguinal testis is presented.
View Article and Find Full Text PDFPlasma concentration of MMP-17 is elevated in boys with cryptorchidism and correlates with HSP-70.
Sci Rep
January 2025
Department of Pediatric Surgery and Urology, Medical University of Bialystok, Waszyngtona 17, 15-274, Bialystok, Poland.
Cryptorchidism, the absence of one or both testicles in the scrotum, is the most common anomaly of genitourinary tract in males. The pathogenesis of undescended testes is unknown however the role of inflammation, tissue remodeling and oxidative stress is postulated. The aim of this study was to explore the role of HSP-70, MMP-3, MMP-17 and IL-8 in possible pathogenic pathways connected with cryptorchidism.
View Article and Find Full Text PDFAbnormal H3K27me3 underlies degenerative spermatogonial stem cells in cryptorchid testis.
Development
January 2025
Department of Histology and Cell Biology, Yokohama City University School of Medicine, Yokohama 236-0004, Japan.
Article Synopsis
- Cryptorchidism is a common congenital condition in newborn males where one or both testes fail to descend into the scrotum, leading to potential infertility due to azoospermia.
- Research using a mouse model of surgically induced cryptorchidism revealed changes in the epigenetic markers H3K27me3 and H3K9me3 in spermatogonial cells, with a specific loss of H3K27me3 linked to gene activation related to development and apoptosis.
- The study indicates that elevated temperatures may enhance the activity of enzymes that demethylate H3K27, contributing to mRNA dysregulation and potentially impacting spermatogonial function.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!