Utility of the Department of Defense Serum Repository in Assessing Deployment Exposure.

J Occup Environ Med

Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, Bethesda, Maryland (Dr Lushniak); Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon); and U.S. Army Public Health Center (Provisional), Aberdeen Providing Ground, Maryland (Dr Gaydos).

Published: August 2016

AI Article Synopsis

  • The research project aimed to showcase how the Department of Defense Serum Repository can be useful for studying environmental exposures during military deployments.
  • The study reviewed the history of deployment exposure tracking and highlighted the need for validated biomarkers found in blood samples, comparing deployed service members with non-deployed controls.
  • The findings indicated the discovery of new serum biomarkers linked to deployment exposures, though their connection to health outcomes was only weakly established, suggesting more research is needed to confirm their effectiveness.

Article Abstract

Objective: This paper describes why the research project was conducted in terms of demonstrating the utility of the Department of Defense Serum Repository in addressing deployment environmental exposures.

Methods: The history deployment exposure surveillance was reviewed and the rationale for developing validated biomarkers that were detected in sera in postdeployment samples and compared with nondeployed controls was described. The goal was to find validated biomarkers that are associated with both exposures and health outcomes.

Results: The articles in this supplement described novel serum biomarkers that were found to be associated with deployment exposures and weakly associated with some health outcomes.

Conclusions: Future research must continue to validate the use of serum biomarkers when operational contingencies prevent the gold standard collection of real-time breathing zone samples in deployed service members.

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Source
http://dx.doi.org/10.1097/JOM.0000000000000796DOI Listing

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