The paper describes a rare clinical case of intramedullary melanocytoma, provides a detailed description of a pathomorphological study, and addresses the issues of differential diagnosis and surgical treatment.
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A 13-Year-Old Girl Affected by Melanocytic Tumors of the Central Nervous System-The Case.
Int J Mol Sci
September 2024
Department of Neurosurgery, Institute of Polish Mother's Health Centre in Lodz, Rzgowska 281/289, 93-338 Lodz, Poland.
Primary intracranial melanoma is a very rare brain tumor, especially when accompanied by benign intramedullary melanocytoma. Distinguishing between a primary central nervous system (CNS) lesion and metastatic melanoma is extremely difficult, especially when the primary cutaneous lesion is not visible. Here we report a 13-year-old girl admitted to the Neurosurgery Department of the Institute of Polish Mother's Health Centre in Lodz due to upper limb paresis.
View Article and Find Full Text PDFUnsatisfactory Neurological Outcome in an Intramedullary Thoracic Intermediate-Grade Melanocytoma-Systematic Review and Illustrative Case.
Cancers (Basel)
May 2024
Department of Neurosurgery, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, 00168 Rome, Italy.
Background: Intramedullary melanocytomas are exceedingly rare, with only twenty-four cases reported up to now. They present as local invasive tumors despite their benign biological behavior. Attempting a complete safe resection often results in severe post-operative neurological deficits, as in our case presented here.
View Article and Find Full Text PDFPrimary Spinal Intradural Melanocytoma of the Thoracic Region: A Rare Case.
Cureus
June 2023
Department of Medicine, Combined Military Hospital (CMH) Lahore Medical College and Institute of Dentistry, Lahore, PAK.
Article Synopsis
- Primary spinal melanocytoma (PSM) is a rare tumor, with only 70 cases documented so far, primarily located in the cervical region of the spine.
- The report discusses a specific case involving a 35-year-old man who had an intramedullary melanocytoma with a component growing outward from the spinal cord.
- Initially, the tumor was accessed surgically, but the operation was halted because it was considered an unusual condition and deemed complex to manage.
Intradural extramedullary meningeal melanocytoma: a case report and literature review.
J Surg Case Rep
January 2023
Department of Neurosurgery, Queens Hospital Romford, London, UK.
Primary meningeal melanocytomas are extremely rare, benign tumours arising from the leptomeninges. While they are considered to be benign lesions, there is potential for their growth and transformation into malignant melanomas. They are commonly found in the cervical spine, with a decreased incidence in the thoracic and lumbar regions.
View Article and Find Full Text PDFPrimary meningeal melanoma masquerading as neurofibromatosis type 2: illustrative case.
J Neurosurg Case Lessons
November 2021
Departments of Pathology and Laboratory Medicine.
Background: Primary meningeal melanocytic neoplasms are exceedingly rare tumors, representing only 0.06% to 0.1% of all primary brain tumors and ranging in spectrum from benign localized tumors to highly aggressive malignant lesions.
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