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Development and validation of recombinant A27L based indirect-ELISA for Sheeppox and Goatpox disease in India.
Vet Res Commun
January 2025
ICAR-National Institute of Veterinary Epidemiology and Disease Informatics (NIVEDI), Post Box No. 6450, Yelahanka, Bengaluru, Karnataka, 560119, India.
Sheeppox and Goatpox are highly contagious transboundary viral diseases of sheep and goats caused by Capripoxvirus, respectively. This study describes the development of indirect ELISA and its serodiagnostic potential as an alternative to the gold standard serum neutralization test (SNT). The homologue of vaccinia virus, ORF 117 (A27L) gene of the Romanian Fenner (RF) strain of Sheeppox virus (SPPV) was used for producing the full-length recombinant A27L (rA27L) protein (∼22 kDa) in a prokaryotic expression system.
View Article and Find Full Text PDFAssessment of Vaccination Impact in PPR-Control Program Implemented in Southern States of India: A System Dynamics Model Approach.
Viruses
December 2024
International Livestock Research Institute (ILRI), Block-C, First Floor, NASC Complex, CG Centre, DPS Marg, Pusa, New Delhi 110012, India.
Mass vaccination against peste des petits ruminants (PPR) in two southern states of India, namely Andhra Pradesh and Karnataka, has reduced disease outbreaks significantly. The sporadic outbreaks reported now can be attributed in part to the recurring movement of sheep and goats between these contiguous states. This study assessed the present level of economic burden and impact of vaccination on the local system (one state), considering the exposure from the external system (neighboring state) using a system dynamic (SD) model.
View Article and Find Full Text PDFThe Global Burden of Emerging and Re-Emerging Orbiviruses in Livestock: An Emphasis on Bluetongue Virus and Epizootic Hemorrhagic Disease Virus.
Viruses
December 2024
School of Veterinary Medicine, Murdoch University, Perth, WA 6150, Australia.
Bluetongue virus (BTV) and epizootic hemorrhagic disease virus (EHDV) are vector-borne orbiviruses that pose an emerging threat to livestock, including cattle and sheep. This review summarizes the global distribution, genetic diversity, and key factors driving their spread along with the existing knowledge gaps and recommendations to mitigate their impact. Both viruses cause hemorrhagic disease in susceptible ruminants and are commonly reported in tropical and subtropical regions including North America, Asia, Africa, Oceania, and some parts of Europe.
View Article and Find Full Text PDFPosterior Positivity Distribution Analysis of Subclinical Bluetongue in the Eastern and North-Eastern States of India: A Wakeup Call for Outbreak Preparedness.
Viruses
December 2024
Centre for Cosmology, Astrophysics and Space Science (CCASS), GLA University, Mathura 281 406, Utter Pradesh, India.
Bluetongue (BT) is considered endemic in the southern states of India, with sporadic incidences reported from the northern, western and central parts of India. However, the eastern and north-eastern states of India have not experienced active disease so far. In the recent past, an extensive sero-epidemiological investigation was carried out in the eastern and north-eastern Indian states.
View Article and Find Full Text PDFSpecies in Dromedary Camels () and Ruminants from Somalia.
Pathogens
January 2025
Vector-Borne Diseases Laboratory, Department of Veterinary Medicine, Universidade Federal do Paraná, Curitiba 80035-050, Brazil.
Ehrlichioses, caused by species, are tick-borne diseases (TBDs) that affect animals and humans worldwide. This study aimed to investigate the molecular occurrence of spp. in 530 animals (155 Dromedary camels, 199 goats, 131 cattle, and 45 sheep) in the Benadir and Lower Shabelle regions of Somalia.
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