X-ray spectral microanalysis was applied to study Ca and P contents in superficial, intermedial and deep enamelum zones in 15 human teeth with different fluorosis manifestations which were extracted for orthodontic purposes. In 3rd grade fluorosis, detected were a statistically reliable decrease in Ca content in enamelum superficial zone and a tendency of its depleting in deep zones. Ca/P ratio was also lowered that indicated mineralization impairment in solid tissues of the teeth. This should affect the choice of the technique of therapy and prevention of different manifestations of teeth fluorosis.
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