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Family-based Helicobacter pylori infection control and management strategy and screen-and-treat strategy are highly cost-effective in preventing multiple upper gastrointestinal diseases in Chinese population at national level.
Helicobacter
June 2024
Department of Gastroenterology and Hepatology, Henan University People's Hospital, and Henan Provincial People's Hospital, Zhengzhou, China.
Background: The overall benefits of the newly introduced family-based Helicobacter pylori (H. pylori) infection control and management (FBCM) and screen-and-treat strategies in preventing multiple upper gastrointestinal diseases at national level in China have not been explored. We investigate the cost-effectiveness of these strategies in the whole Chinese population.
View Article and Find Full Text PDFSaccharomyces boulardii combined with triple therapy alter the microbiota in the eradication of Helicobacter pylori infection.
Sci Rep
June 2024
Department of Gastroenterology, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, 210006, People's Republic of China.
To assess the effectiveness and safety of combining Saccharomyces boulardii powder with triple therapy as a primary approach for eradicating H. pylori infection, a total of 144 patients who tested positive for H. pylori and diagnosed with non-ulcer dyspepsia underwent endoscopy at two national centers between June 2017 and March 2019 were included.
View Article and Find Full Text PDFCo-Morbidities of Irritable Bowel Syndrome in a Racially and Ethnically Diverse Population.
J Clin Med
March 2024
Section of Gastroenterology & Hepatology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
: Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction (DGBI), and associated co-morbidities worsen quality of life. Research concerning IBS co-morbidities in different racial/ethnic groups is very sparse. This study aimed to determine the prevalence rates of co-morbidities and possible differences in a multiracial/ethnic IBS cohort.
View Article and Find Full Text PDFDevelopment of a gastric cancer risk calculator for questionnaire-based surveillance of Iranian dyspeptic patients.
BMC Gastroenterol
January 2024
HPGC Research Group, Department of Medical Biotechnology, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran.
Background: Gastric cancer (GC) is considered a silent killer, taking more than three quarters of a million lives annually. Therefore, prior to further costly and invasive diagnostic approaches, an initial GC risk screening is desperately in demand.
Methods: In order to develop a simple risk scoring system, the demographic and lifestyle indices from 858 GC and 1132 non-ulcer dyspeptic (NUD) patients were analysed.
Recurrence of Helicobacter pylori following successful eradication and clinical outcomes in Korean patients.
Helicobacter
January 2024
Department of Internal Medicine, St. Vincent Hospital, The Catholic University of Korea, Suwon, South Korea.
Article Synopsis
- Helicobacter pylori infections can either recur due to recrudescence or reinfection, and there are no established guidelines for treatment after recurrence.
- A study involving 996 patients from 2017 to 2022 found that the rates of recrudescence and reinfection were low at 3.9% and 3.7%, respectively, but reinfection was notably higher in patients with non-ulcer dyspepsia.
- The effectiveness of standard triple therapy for treating reinfection was limited, with higher success rates observed in second-line therapies, highlighting the need for further research on effective treatment strategies for this group.
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