The benefits of “bet‐hedging” strategies have been assumed to be the main cause of phenotypic diversity in biological populations. However, in their recent work, Healey (2016) provide experimental support for negative frequency‐dependent selection (NFDS) as an alternative driving force of diversity. NFDS favors rare phenotypes over common ones, resulting in an evolutionarily stable mixture of phenotypes that is not necessarily optimal for population growth.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119495 | PMC |
| http://dx.doi.org/10.15252/msb.20167133 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Volumetric Passive Acoustic Mapping and Cavitation Detection of Nanobubbles under Low-Frequency Insonation.
ACS Mater Au
January 2025
Department of Biomedical Engineering, Tel Aviv University, Tel Aviv 6997801, Israel.
Gas bubbles, commonly used in medical ultrasound (US), witness advancements with nanobubbles (NB), providing improved capabilities over microbubbles (MB). NBs offer enhanced penetration into capillaries and the ability to extravasate into tumors following systemic injection, alongside prolonged circulation and persistent acoustic contrast. Low-frequency insonation (<1 MHz) with NBs holds great potential in inducing significant bioeffects, making the monitoring of their acoustic response critical to achieving therapeutic goals.
View Article and Find Full Text PDFMitochondrial DNA mutations in human oocytes undergo frequency-dependent selection but do not increase with age.
bioRxiv
December 2024
Department of Biology, Penn State University, University Park, PA 16802, USA.
Mitochondria, cellular powerhouses, harbor DNA (mtDNA) inherited from the mothers. MtDNA mutations can cause diseases, yet whether they increase with age in human germline cells-oocytes-remains understudied. Here, using highly accurate duplex sequencing of full-length mtDNA, we detected mutations in single oocytes, blood, and saliva in women between 20 and 42 years of age.
View Article and Find Full Text PDFMetapopulation heterogeneities in host mobility, productivity, and immunocompetency always increase virulence and infectiousness.
Proc Natl Acad Sci U S A
December 2024
Complexity Science and Evolution Unit, Okinawa Institute of Science and Technology Graduate University (OIST), Tancha, Onna, Kunigami, Okinawa 904-0495, Japan.
The epidemiology and evolution of diseases unfold in populations that are rarely homogeneous. Instead, hosts infected by pathogens often form metapopulations, in which local populations connected by the movement of hosts experience different demographic and epidemiological conditions. Here, we develop a general theory of the evolution of pathogens in heterogeneous metapopulations.
View Article and Find Full Text PDF3D-printed acoustic metasurface with encapsulated micro-air-bubbles for frequency-selective manipulation.
Lab Chip
January 2025
College of Engineering and Applied Sciences, Nanjing University, Jiangsu 210093, China.
Acoustic waves provide an effective method for object manipulation in microfluidics, often requiring high-frequency ultrasound in the megahertz range when directly handling microsized objects, which can be costly. Micro-air-bubbles in water offer a solution toward low-cost technologies using low-frequency acoustic waves. Owing to their high compressibility and low elastic modulus, these bubbles can exhibit significant expansion and contraction in response to even kilohertz acoustic waves, leading to resonances with frequencies determined and tuned by air-bubble size.
View Article and Find Full Text PDFProficient trigonometrical-fitted two-derivative multistep collocation methods in predictor-corrector approach: Application to perturbed Kepler problem.
MethodsX
December 2024
Institute for Mathematical Research, Universiti Putra Malaysia, 43400 UPM, Serdang, Malaysia.
An efficient trigonometrical-fitted two-derivative multistep collocation (TF-TDMC) method using Legendre polynomials up to order five as the basis functions, has been developed for solving second-order ordinary differential equations with oscillatory solution effectively. Interpolation method of approximated power series and collocation technique of its second and third derivative are implemented in the construction of the methods. Two-derivative multistep collocation methods are developed in predictor and corrector form with varying collocation and interpolation points.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!