Relationship between muscle strength and motor function in Duchenne muscular dystrophy.

Arq Neuropsiquiatr

Universidade de São Paulo, Faculdade de Medicina, Departamento de Fisioterapia, Fonoaudiologia e Terapia Ocupacional, São Paulo SP, Brasil;

Published: July 2016

Objective: To investigate the relationship between muscle strength and motor function and between these variables and age.

Method: Muscle strength was measured by Medical Research Council (MRC) scale and motor function, by Motor Function Measure (MFM), in 40 non-ambulatory patients. Spearman tests investigated the relationships between muscle strength, motor function and age.

Results: Total MRC and MFM scores were strongly related to each other (r = 0.94; p < 0.001), but not to age (r = -0.19, r = -0.31, respectively; p > 0.05). Strong and moderate relationships between partial muscle strength and motor function scores were found. Higher correlation coefficients were found between total scores and Dimensions 2 (axial/ proximal control) and 3 (distal control) of MFM.

Conclusion: Muscle strength and motor function are strongly correlated and seem to decrease proportionally in DMD.

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Source
http://dx.doi.org/10.1590/0004-282X20160085DOI Listing

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