Objectives: To determine the efficacy of hybrid external fixation in the treatment of tibial pilon fractures.
Design: Retrospective, multicentre study.
Patients/participants: Adult patients with tibial pilon fractures treated with hybrid external fixation.
Intervention: Fracture reduction with ligamentotaxis and fixation with XCaliber hybrid external fixator.
Main Outcome Measurements: Fracture union, complications, functional outcome (Mazur Ankle Score).
Results: Union was obtained in 159 fractures at an average of 125days; there were three delayed unions and three non-unions. The most frequent complication was superficial pin-track infections (48), all of which responded to local wound care and antibiotics. There were no deep infections and no DVT. Only one fracture had loss of reduction that required frame revision. The overall functional scores were 91 (excellent) for AO/OTA type A fractures, 89 (good) for type B fractures, and 75 (satisfactory) for type C fractures.
Conclusions: Hybrid external fixation is an effective method of stabilising tibial pilon fractures, particularly those with marked comminution. The minimally-invasive technique and stable fixation enable early mobilisation, with good functional results and minimal complications.
Level Of Evidence: Level IV Case series.
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http://dx.doi.org/10.1016/j.injury.2016.07.045 | DOI Listing |
Nanomaterials (Basel)
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Biohybrid Systems Research Center (BSRC), Inha University, 100 Inha-ro, Michuhol-gu, Incheon 22212, Republic of Korea.
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View Article and Find Full Text PDFEntropy (Basel)
January 2025
Department of Mechanical and Aerospace Engineering, The University of Manchester, Manchester M1 3PL, UK.
This study investigates the flow field around a finite rectangular prism using both experimental and computational methods, with a particular focus on the influence of the turbulence approach adopted, the mesh resolution employed, and different subgrid length scales. Ten turbulence modelling and simulation approaches, including both 'scale-modelling' Reynolds-Averaged Navier-Stokes (RANS) models and 'scale-resolving' Delayed Detached Eddy Simulation (DDES), were tested across six different mesh resolutions. A case with sharp corners allows the location of the flow separation to be fixed, which facilitates a focus on the separated flow region and, in this instance, the three-dimensional interaction of three such regions.
View Article and Find Full Text PDFHered Cancer Clin Pract
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Division of Cancer and Genetics, Cardiff University School of Medicine, Heath Park, Cardiff, CF14 4XN, UK.
Carcinogenesis encompasses processes that lead to increased mutation rates, enhanced cellular division (tumour growth), and invasive growth. Colorectal cancer (CRC) carcinogenesis in carriers of pathogenic APC (path_APC) and pathogenic mismatch repair gene (path_MMR) variants is initiated by a second hit affecting the corresponding wild-type allele. In path_APC carriers, second hits result in the development of multiple adenomas, with CRC typically emerging after an additional 20 years.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Mathematics and Statistics, College of Science, Taif University, P.O. Box 11099, 21944, Taif, Saudi Arabia.
The monkeypox virus (MPXV), which is a member of the Orthopoxvirus genus in the class Poxviridae, is the causative agent of the zoonotic viral infection MPXV. The disease is similar to smallpox, but it is usually less dangerous. This study examines the evolution of the MPXV epidemic in Canada with an emphasis on the effects of control employing actual data.
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