The evolving role of adiponectin as an additive biomarker in HFrEF.

Heart Fail Rev

Laboratory for Cellular and Molecular Cardiology, Department of Cardiology, Antwerp University Hospital, Edegem, Belgium.

Published: November 2016

AI Article Synopsis

  • Heart failure (HF) is becoming a bigger health issue, and more people are expected to develop it in the future.
  • New research shows that a protein called adiponectin can help the heart but may also contribute to heart failure problems.
  • The review looks at how adiponectin helps protect the heart and fight inflammation, and discusses its potential to help diagnose and predict heart failure outcomes.

Article Abstract

Heart failure (HF) is a growing health problem. Despite improved management and outcome, the number of patients with HF is expected to keep rising in the following years. In recent research, adiponectin was shown to exert beneficial effects in the cardiovascular system, but the protein was also implicated in the development and progression of HF. The objective of this review is to provide an overview of current knowledge on the role of adiponectin in HF with reduced ejection fraction. We discuss the cardioprotective and (anti-) inflammatory actions of adiponectin and its potential use in clinical diagnosis and prognosis.

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Source
http://dx.doi.org/10.1007/s10741-016-9578-zDOI Listing

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