Paliperidone Induced Hypoglycemia by Increasing Insulin Secretion.

Case Rep Psychiatry

Department of Psychiatry, Osaka General Medical Center, 3-1-56 Bandai-higashi, Sumiyoshi, Osaka 5588558, Japan.

Published: August 2016

We report the case of a 41-year-old woman with schizophrenia who developed persistent hypoglycemia following paliperidone administration. After discontinuing paliperidone, the hypoglycemia resolved, but symptoms of diabetes emerged. Therefore, it appears that the hypoglycemia induced by paliperidone may mask symptoms of diabetes. Paliperidone may induce hypoglycemia by increasing insulin secretion. This report could help elucidate the relationship between atypical antipsychotics and glucose metabolism.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958443PMC
http://dx.doi.org/10.1155/2016/1805414DOI Listing

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