The Authors, after briefly the classification of neonatal thrombocytopenia (NT) and the causes Autoimmune Neonatal Thrombocytopenia (AINT), present the case of thrombocytopenic purpura in a neonate born of a mother affected by asynptomathic idiopathic thrombocytopenic purpura (PTI). The AINT diagnosis, suspected on the basis of the clinical state, is confirmed either by the presence in the mother's serum of free antibody antiplatelet, or measurement of maternal platelet associated IgG (PAIgG). In conclusion the Authors report the management in the case of neonates at "risk" for AINT.

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