Various time-varying algorithms have been applied in multichannel sound systems to improve the system's stability and, among these, frequency shifting has been demonstrated to reach the maximum stability improvement achievable by time-variation in general. However, the modulation artifacts have been found to diminish the gain improvement unusable for a higher number of channels and high-quality applications such as music reproduction. This paper proposes alternatively time-varying mixing matrices, which is an efficient algorithm corresponding to symmetric up and down frequency shifting. It is shown with a statistical approach that time-varying mixing matrices can as well achieve maximum stability improvement for a higher number of channels. A listening test demonstrates the improved quality of time-varying mixing matrices over frequency shifting.
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http://dx.doi.org/10.1121/1.4955285 | DOI Listing |
MethodsX
June 2025
Department of Statistics, Faculty of Science and Data Analytics, Institut Teknologi Sepuluh Nopember, Surabaya 60111, Indonesia.
This article proposed a simultaneous equation model for small area estimation with random area and time-varying effects called the Simultaneous Equation Rao-Yu (SERY) model. In the context of small area estimation, many socioeconomic variables are likely to exhibit not only correlations but also causal relationships. Therefore, it is considered to use simultaneous equation model for indirect estimation method in a small-area.
View Article and Find Full Text PDFCell Rep
January 2025
Western Institute for Neuroscience, Western University, London, ON, Canada; Department of Clinical Neurological Sciences, London Health Sciences Centre, Western University, London, ON, Canada; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. Electronic address:
Neuronal populations expand their information-encoding capacity using mixed selective neurons. This is particularly prominent in association areas such as the lateral prefrontal cortex (LPFC), which integrate information from multiple sensory systems. However, during conditions that approximate natural behaviors, it is unclear how LPFC neuronal ensembles process space- and time-varying information about task features.
View Article and Find Full Text PDFAnn Work Expo Health
January 2025
Department of Environmental Health and Engineering, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD 21205, United States.
The use of peracetic acid (PAA) as a general disinfectant has seen increasing usage in recent years, and although it is a strong irritant, exposure monitoring for PAA may often be difficult due to relatively high costs and the potential for interferences by other co-occurring chemicals such as hydrogen peroxide. These issues with exposure monitoring make modeling a potentially useful tool in exposure assessment of PAA if model parameters can be accurately determined. This study estimates the time-varying mass emission rate of PAA for use in exposure modeling by using the small spill model and examines the effect of various environmental conditions on the PAA evaporation rate, including surface roughness/substrate, general ventilation rate, and local wind speed.
View Article and Find Full Text PDFEpidemiology
December 2024
Department of Global Health, School of Public Health, Wuhan University, 115# Donghu Road, Wuhan, 430071, China.
Background: Anemia is common among HIV/AIDS patients, impacting prognosis. Particulate matter (PM) exposure is an understudied, potentially modifiable risk factor in this group.
Methods: We gathered 36,266 hemoglobin (Hb) measurements from 6,808 HIV/AIDS patients from the HIV/AIDS Comprehensive Response Information Management System from January 1, 2004, to December 31, 2021.
Clin Transl Sci
January 2025
Qilu Pharmaceutical Co., Ltd, Jinan, Shandong, China.
Iruplinalkib (WX-0593), a selective oral ALK/ROS1 tyrosine kinase inhibitor, was approved in China as first-line therapy for ALK-positive non-small-cell lung cancer (NSCLC) and for the treatment of locally advanced or metastatic ALK-positive NSCLC that has progressed following crizotinib therapy. Pharmacokinetics (PK) data of iruplinalkib have been collected in healthy subjects and patient populations in several studies. We developed a population PK (PopPK) model for describing iruplinalkib plasma concentrations and for evaluating whether dose adjustments are necessary based on demographic factors or disease characteristics.
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