Background: In studies employing physiological measures such as magnetic resonance imaging (MRI), it is often hard to distinguish what constitutes risk-resilience factors to posttraumatic stress disorder (PTSD) following trauma exposure and what the effects of trauma exposure and PTSD are.
Objective: We aimed to investigate whether there were observable morphological differences in cortical and sub-cortical regions of the brain, 7-8 years after a single potentially traumatic event.
Methods: Twenty-four participants, who all directly experienced the 2004 Indian Ocean Tsunami, and 25 controls, underwent structural MRI using a 3T scanner. We generated cortical thickness maps and parcellated sub-cortical volumes for analysis.
Results: We observed greater cortical thickness for the trauma-exposed participants relative to controls, in a right lateralized temporal lobe region including anterior fusiform gyrus, and superior, middle, and inferior temporal gyrus.
Conclusions: We observed greater thickness in the right temporal lobe which might indicate that the region could be implicated in resilience to the long-term effects of a traumatic event. We hypothesize this is due to altered emotional semantic memory processing. However, several methodological and confounding issues warrant caution in interpretation of the results.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055608 | PMC |
| http://dx.doi.org/10.3402/ejpt.v7.31314 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Identifying Settler Colonial Determinants of Indigenous Health Within the United States: A Discursive Paper.
Public Health Nurs
December 2024
School of Nursing, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Aim(s): This discursive article aims to examine how systemic factors (both) reproduce the structure of settler colonialism and influence health outcomes among Indigenous peoples in the United States through settler colonial determinants of Indigenous health (SCDoIH).
Design: Discursive paper.
Methods: This discursive paper demonstrates how settler colonialism and health relate to each other within a nursing context.
Patient- and Family-Centered Outcomes After Intensive Care Unit Admission.
Am J Crit Care
January 2025
Eliotte L. Hirshberg is an assistant professor of pediatrics, Shock Trauma Intensive Care Unit, Intermountain Medical Center, Murray, Utah; Center for Humanizing Critical Care, Intermountain Health, Murray, Utah; Pulmonary and Critical Care Medicine, Intermountain Medical Center, Salt Lake City, Utah; and Pulmonary and Critical Care Medicine, University of Utah School of Medicine, Salt Lake City.
Background: Family satisfaction with intensive care is a measure of patient experience and patient-centered care. Among the factors that might influence family satisfaction are the timing of patient admittance to the intensive care unit (ICU), the ICU environment, and individual health care providers.
Objective: To evaluate family satisfaction with the ICU and to explore associations between satisfaction and specific characteristics of the ICU stay.
Associations of Traumatic Brain Injury and Hearing: Results From the Atherosclerosis Risk in Communities Neurocognitive Study (ARIC-NCS).
J Head Trauma Rehabil
December 2024
Author Affiliations: Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (Dr Schneider); Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (Dr Schneider); Department of Psychiatry and Behavioral Sciences, School of Medicine, Johns Hopkins University, Baltimore, Maryland (Dr Kamath); Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland (Drs Reed, Sharrett, Lin, and Deal); The MIND Center, University of Mississippi Medical Center, Jackson, Mississippi (Dr Mosley); National Institute of Neurological Disorders and Stroke Intramural Research Program, Bethesda, Maryland (Dr Gottesman); Department of Otolaryngology, School of Medicine, Johns Hopkins University, Baltimore, Maryland (Drs Lin and Deal); and Cochlear Center for Hearing and Public Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (Drs Lin and Deal).
Objective: To examine associations of traumatic brain injury (TBI) with self-reported and clinical measures of hearing function.
Setting: Four US communities.
Participants: A total of 3176 Atherosclerosis Risk in Communities Study participants who attended the sixth study visit in 2016-2017, when hearing was assessed.
UCF-101 ameliorates traumatic brain injury by promoting microglia M2 polarization via AMPK/NF-κB pathways in LPS-induced BV2 cells.
J Mol Histol
December 2024
Department of Neurosurgery, Quzhou People's Hospital, No. 100, Minjiang Avenue, High-speed Rail, New City, Quzhou, Zhejiang, China.
Traumatic brain injury (TBI) is a common neurosurgical emergency. As a macrophage in brain, microglia involves in secondary TBI injury. UCF-101, an Omi/HtrA2 inhibitor, protects against neurological disorders.
View Article and Find Full Text PDFUnveiling the neglected role of the intensity of acute stress disorder in the prediction of full- and sub-threshold posttraumatic stress disorder: looking beyond the diagnosis.
Soc Psychiatry Psychiatr Epidemiol
December 2024
School of Psychology, University of New South Wales, Sydney, NSW, 2052, Australia.
Purpose: Exposure to traumatic events may lead to the development of Acute Stress Disorder (ASD) within the first month post-trauma in some individuals, while others may not exhibit ASD symptoms. ASD was introduced as a potential early indicator to identify those at higher risk of developing Posttraumatic Stress Disorder (PTSD), however, PTSD can occur in some individuals even without prior ASD. Assessing ASD post-trauma can assist in identifying those who would most benefit from intervention to prevent later PTSD, yet the predictive power of ASD varies across studies, with intensity of ASD symptoms and subthreshold PTSD often less considered.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!