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Using Active and Passive Smartphone Data to Enhance Adolescents' Emotional Awareness in Forensic Outpatient Setting: A Qualitative Feasibility and Usability Study.
JMIR Form Res
December 2024
Child and Adolescent Psychiatry & Psychosocial Care, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands.
Background: Delinquent behavior in adolescence is a prevalent issue, often associated with difficulties across multiple life domains, which in turn perpetuates negative life outcomes. While current treatment programs show partial success in improving behavioral changes and reducing recidivism, comprehensive conclusions regarding the overall efficacy of these interventions have yet to be established. In forensic outpatient settings, the discrepancy between adolescents' limited emotional awareness and the predominant emphasis on cognitive reflection, combined with low treatment adherence, may be factors that undermine treatment efficacy.
View Article and Find Full Text PDFSmartphone-integrated colorimetric sensor for rapid detection of phenolic compounds based on the peroxidase-mimicking activity of copper/cerium-aspartic acid metal-organic framework.
Mikrochim Acta
January 2025
Department of Pulmonary and Critical Care Medicine, Quzhou People's Hospital, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, 324000, China.
A smartphone-integrated colorimetric sensor is introduced for the rapid detection of phenolic compounds, including 8-hydroquinone (HQ), p-nitrophenol (NP), and catechol (CC). This sensor relies on the peroxidase-mimicking activity of aspartate-based metal-organic frameworks (MOFs) such as Cu-Asp, Ce-Asp, and Cu/Ce-Asp. These MOFs facilitate the oxidation of a colorless substrate, 3,3',5,5'-tetramethylbenzidine (TMB), by reactive oxygen species (ROS) derived from hydrogen peroxide (HO), resulting in the formation of blue-colored oxidized TMB (ox-TMB).
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Amsterdam Neuroscience, Neurodegeneration, Amsterdam, Netherlands.
Article Synopsis
- There’s a growing interest in using smartphone typing behavior as a way to detect early cognitive changes in Alzheimer's Disease.
- Researchers conducted a study with 40 participants across different cognitive states to assess typing behavior over 28 days using a smartphone app.
- Results showed that typing dynamics were reliably linked to cognitive performance, with significant correlations found between typing features and Mini-Mental State Examination scores.
Background: Interest in use of digital technology to advance AD/ADRD research has been growing exponentially over the last few years. This acceleration is fueled in part by growing awareness that both well used research methods as well as newer biomarker approaches are 1) inadequate for clinical symptom detection in the earliest stages of an insidious onset disease and 2) have resulted in inaccurate as well as biased data that is generating treatment and prevention solutions that are insufficiently relevant to some and potentially not relevant to many.
Methods: Sensors embedded in mobile devices such as smartphones and wearables deliver a high penetration, low-cost solution for overcoming previous limitations of early detection sensitivity and limited representative reach.
Clinical Manifestations.
Alzheimers Dement
December 2024
University of California Los Angeles, Los Angeles, CA, USA.
Background: Unsupervised high-frequency cognitive-ecological momentary assessment (EMA) on smartphones is increasingly used to assess preclinical risk for Alzheimer's disease and related dementias (ADRD). While these tests are reliable and valid for individuals with preclinical ADRD, it is unclear whether administering cognitive EMAs to people living with ADRD is feasible and valid. Our study explored the feasibility and validity on cognitive EMA tests in people living with moderate to severe ADRD.
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