In this paper, AuNPs@Polyethyleneimine-derived carbon hollow spheres were synthesized by a versatile and facile method in three steps and successfully developed and validated as Amitriptyline sensor using cyclic voltammetry (CV), chronoamperometry (CA) and differential pulse voltammetry (DPV) methods. The characterization of the electrode surface has been carried out by means of scanning electron microscopy (SEM), transmission electron microscopy (TEM), x-ray diffraction (XRD), x-ray photo-electron spectrum (XPS), electrochemical impedance spectroscopy (EIS) and chronocoulometry (CC). The obtained negatively charged modified electrode was highly selective to Amitriptyline and it was shown a wide linear range from 0.1 to 700μmolL(-1), with a lower detection limit of 0.034μmolL(-1) (n=5, S/N=3), revealing the high-sensitivity properties. The modified electrode is used to achieve the real-time quantitative detection of AMT for biological applications, and satisfactory results are obtained. Due to the advantages of the sensor, its selectivity, sensitivity and stability, it will have a bright future in the field of medical diagnosis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bios.2016.07.028 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Climate change impact on green spaces planning in an urban area using a hybrid approach.
Environ Sci Pollut Res Int
January 2025
Department of Geomatics Engineering, Hacettepe University, 06800, Beytepe, Ankara, Türkiye.
This study presents a hybrid methodology for planning green spaces to enhance urban sustainability and livability, evaluating the impacts of climate change on cities. Cities, once accommodating a small population, have become major centers of migration and development since the eighteenth century. Rapid urban growth intensifies infrastructure, environmental, and social challenges.
View Article and Find Full Text PDFThermophysical analysis of time-dependent magnetized Casson hybrid nanofluid flow (Cu + GO/Kerosene Oil) using Darcy-Forchheimer and thermal radiative models for industrial cooling applications.
Sci Rep
January 2025
College of Engineering, Applied Science University (ASU), Manama, Kingdom of Bahrain.
This paper presents an in-depth analytical investigation into the time-dependent flow of a Casson hybrid nanofluid over a radially stretching sheet. The study introduces the effects of magnetic fields and thermal radiation, along with velocity and thermal slip, to model real-world systems for enhancing heat transfer in critical industrial applications. The hybrid nanofluid consists of three nanoparticles-Copper and Graphene Oxide-suspended in Kerosene Oil, selected for their stable and superior thermal properties.
View Article and Find Full Text PDFPh3P-I2-mediated Syntheses of C-12 Carboxamide Indoloquinazolines and 2-Aminosubstituted-indol-3-ones from Isatins and Amines.
Chem Asian J
January 2025
Chiang Mai University, Chemistry, 239 Huay Kaew Road, Muang District, 50200, Chiang Mai, THAILAND.
The Ph3P-I2-mediated reactions between isatins and amines were extensively investigated leading to the discovery of highly selective and divergent routes toward the synthesis of two distinct classes of indole-based frameworks. Through a strategic design of the reaction paths, we overcome potential side reactions to achieve convenient and straightforward one-pot methods to access either indoloquinazolines with C-12 carboxamide or 2-aminosubstituted indol-3-ones using the same reagent system. Mechanistic studies reveal the role of Ph3P-I2 in governing product selectivity, providing an efficient route to novel fused-indolone derivatives with promising applications in drug discovery and medicinal chemistry.
View Article and Find Full Text PDFmicrobiota model recapitulates and predicts individualised sensitivity to dietary emulsifier.
Gut
January 2025
Microbiome-Host Interactions, INSERM U1306, CNRS UMR6047, Institut Pasteur, Université Paris Cité, Paris, France
Background: Non-absorbed dietary emulsifiers, including carboxymethylcellulose (CMC), directly disturb intestinal microbiota, thereby promoting chronic intestinal inflammation in mice. A randomised controlled-feeding study (Functional Research on Emulsifiers in Humans, FRESH) found that CMC also detrimentally impacts intestinal microbiota in some, but not all, healthy individuals.
Objectives: This study aimed to establish an approach for predicting an individual's sensitivity to dietary emulsifiers via their baseline microbiota.
Jigsaw technique: Will it help Gen Z nursing students?
Adv Physiol Educ
January 2025
Department of Physiology, Government medical college and hospital, Sector 32 Chandigarh, India.
This research focuses on Generation Z (Gen Z) students, specifically those in nursing colleges. Gen Z individuals display unique characteristics in terms of thinking, personality, lifestyle, and learning preferences compared to preceding generations, necessitating adaptations in teaching methodologies within nursing schools. This study explores the effectiveness of the Jigsaw Technique (JST) in engaging first-year undergraduate nursing students in learning process.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!