Purpose Of Review: Measuring clinically relevant and patient-centered perioperative outcomes provides the knowledge that enables clinicians to optimize their practice and guide shared decision-making, researchers to set a future agenda and policymakers to prioritize healthcare spending.
Recent Findings: A large international collaboration is currently working to define a set of core outcomes for use in perioperative medicine research. Standardizing which outcomes are measured and how they are defined will help ensure that perioperative research output is meaningful and practice changing. The ability to pool nonheterogeneous data from multiple clinical trials will also improve ability of research to provide definitive answers and improve the cost-effectiveness of research spending.
Summary: Future clinical trials in perioperative medicine should utilize clearly defined, validated and standardized patient-centered outcome measures.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1097/ACO.0000000000000383 | DOI Listing |
Front Cardiovasc Med
January 2025
Department of Anesthesiology and Operation, The First Hospital of Lanzhou University, Lanzhou, Gansu, China.
Objective: We aimed to explore the application value of unsupervised machine learning in identifying acute gastrointestinal injury (AGI) after extracorporeal circulation for acute type A aortic dissection (ATAAD).
Methods: Patients who underwent extracorporeal circulation for ATAAD at the First Hospital of Lanzhou University from January 2016 to January 2021 were included. Unsupervised machine learning algorithm was used to stratify patients into different phenogroups according to the similarity of their clinical features and laboratory test results.
J Intensive Med
January 2025
Department of Anesthesia and Perioperative Care, Division of Critical Care Medicine, UCSF, San Francisco, CA, USA.
Acute kidney injury (AKI) presents a significant challenge in the management of critically ill patients, as it is associated with increased mortality, prolonged hospital stays, and increased healthcare costs. In certain conditions, such as during sepsis or after cardiac surgery, AKI is one of the most frequent complications, affecting 30%-50% of patients. Over time, even after the resolution of AKI, it can evolve into chronic kidney disease, a leading global cause of mortality, and cardiovascular complications.
View Article and Find Full Text PDFWorld J Gastrointest Surg
January 2025
General Surgery Center, General Hospital of Western Theater Command, Chengdu 610000, Sichuan Province, China.
Background: Minimally invasive pancreaticoduodenectomy (MIPD) is considered one of the most complex procedures in general surgery. The number of articles on MIPD has been increasing annually. However, published reports often have complex research directions, and the focal points frequently change.
View Article and Find Full Text PDFTransl Perioper Pain Med
August 2020
Department of Anesthesiology and Pain Medicine, University of California Davis Health, Sacramento, California, USA.
Perioperative myocardial injury is frequently caused by tachycardia from excessive sympathetic nervous system activity resulting from the surgical stimulation (type 2) rather than by rupture of atherosclerotic plaques with superimposed thrombosis (type 1). The elevated sympathetic nervous system activity results in tachycardia that induces demand ischemia within the myocardium and damages the heart muscle. A rise in troponin has been shown to be a reliable predictor of adverse cardiovascular events when measured in a population at risk.
View Article and Find Full Text PDFDrug Des Devel Ther
January 2025
Department of Anesthesiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, People's Republic of China.
Purpose: Living kidney transplantation is a common treatment for end-stage renal disease. The impact of anaesthetics on postoperative biomarkers of renal injury in living kidney transplant donors is not well understood.
Patients And Methods: 70 transplant donors who underwent kidney extraction were randomly assigned to following two groups: sevoflurane (S group) and propofol (P group).
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!