AI Article Synopsis

  • Dispersing hydrophobin HFBII using perfluorohexane gas prevents aggregation, keeping sizes at the nanometer level.
  • The presence of fluorocarbon gas leads to a unique co-adsorption effect, significantly enhancing HFBII adsorption at the air/water interface.
  • This method results in uniform spherical microbubbles that are stable and echogenic, with altered film characteristics that prevent solid phase transition.

Article Abstract

Dispersing hydrophobin HFBII under air saturated with perfluorohexane gas limits HFBII aggregation to nanometer-sizes. Critical basic findings include an unusual co-adsorption effect caused by the fluorocarbon gas, a strong acceleration of HFBII adsorption at the air/water interface, the incorporation of perfluorohexane into the interfacial film, the suppression of the fluid-to-solid 2D phase transition exhibited by HFBII monolayers under air, and a drastic change in film elasticity of both Gibbs and Langmuir films. As a result, perfluorohexane allows the formation of homogenous populations of spherical, narrowly dispersed, exceptionally stable, and echogenic microbubbles.

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http://dx.doi.org/10.1002/anie.201603706DOI Listing

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