AI Article Synopsis
- * In 2013, new diagnostic criteria were created to help identify aHUS early and start treatment quickly.
- * Recent research has led to updated definitions and classifications for aHUS, aiming to refine the diagnostic process and treatment options through new algorithms and strategies.
Article Abstract
Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. In 2013, we developed diagnostic criteria to enable early diagnosis and timely initiation of appropriate treatment for aHUS. Recent clinical and molecular findings have resulted in several proposed classifications and definitions of thrombotic microangiopathy and aHUS. Based on recent advances in this field and the emerging international consensus to exclude secondary TMAs from the definition of aHUS, we have redefined aHUS and proposed diagnostic algorithms, differential diagnosis, and therapeutic strategies for aHUS.
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| http://dx.doi.org/10.1111/ped.13044 | DOI Listing |
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