It was established that steroidal genins and their glycosides of the spirostan series and (especially) furostan series show anticestodal activity against Hymeiolepis nana species. Search for anthelminthic agents in the indicated series of compounds is a promising direction of research.
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J Plant Res
January 2025
Botany Unit (SAIF & R), CSIR-CDRI, Sector 10, Jankipuram Extension, Sitapur Road, Lucknow, Uttar Pradesh, 226031, India.
Calotropis procera (Aiton) W.T. Aiton is a medicinal plant belonging to the family Apocynaceae as a core source of natural cardenolides.
View Article and Find Full Text PDFInt J Mol Sci
October 2024
Laboratory of Pharmacognosy, Faculty of Health Sciences, School of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Phytochemical investigation of Sibth. & Sm. resulted in the isolation of twenty-two natural products: eleven sesquiterpene lactones, artemorin (), tamirin (), tanachin (), reynosin (), baynol C (), desacetyl-β-cyclopyrethrosin (), 1β-hydroxy-4α-methoxy-5α,7α,6β-eudesm-11(13)-en-6,12-olide (), 1β,4α,6α-trihydroxyeudesm-11-en-8α,12-olide (), 1β-hydroxy-arbusculin A (), methyl-1β,4α,6α-trihydroxy-5α,7αH-eudesm-11(13)-en-12-oate () and methyl-1β,6α,8α-trihydroxy-5α,7αH-eudesma-4(15),11(13)-dien-12-oate (); one lignan, pinoresinol (); one norisoprenoid, loliolide (); six flavonoids (four genins and two glycosides), hispidulin (), nepetin (), jaceosidin (), eriodictyol (), eriodictyol-3'-O-β-D-glucoside () and eriodictyol-7-O-β-D-glucuronide (); and three phenolic derivatives (one phenolic acid and two phenolic glucosides), protocatechuic acid (), arbutin () and nebrodenside A ().
View Article and Find Full Text PDFPhytomedicine
July 2024
Área Farmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Suipacha 531, Rosario 2000, Argentina. Electronic address:
Mar Drugs
April 2023
Department of Plant, Food, and Environmental Sciences, Faculty of Agriculture, Dalhousie University, Truro, NS B2N 5E3, Canada.
Frondosides are the major saponins (triterpene glycosides) of the North Atlantic sea cucumber (). Frondosides possess amphiphilic characteristics due to the presence of various hydrophilic sugar moieties and hydrophobic genin (sapogenin). Saponins are abundant in holothurians, including in sea cucumbers that are widely distributed across the northern part of the Atlantic Ocean.
View Article and Find Full Text PDFFood Res Int
November 2022
Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Egypt. Electronic address:
In this work, metabolic profiling of the different parts of ground cherry (P. pruinosa) including fruits, calyces, leaves, stems and roots using UPLC-MS/MS analysis combined to chemometric analysis was attempted. A total of 82 chromatographic peaks belonging to different metabolite classes were identified including terpenes, flavonoids genin and glycosides, withanolides, physalins, sucrose esters, fatty acids and other miscellaneous compounds with withanolides being the most predominant class.
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