The signs which one ordinarily associates with gout, such as subcutaneous nodules, podagra, arthritis, and elevation of blood uric acid level, do not necessarily make for a diagnosis of that condition, as Dr Talbott and his associates explain. Gout is still frequently misdiagnosed, in spite of renewed interest in it, because of ignorance of its many facets, which are described in this symposium. One of the most important of these may be the "gouty diathesis" which appears to be associated with significant disease, particularly coronary heart disease.

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