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[18F]Tetrafluoroborate: a new NIS PET/CT radiopharmaceutical. An overview focused on differentiated thyroid cancer.
Eur Thyroid J
January 2025
G Treglia, Repubblica e Cantone Ticino Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Background: In relapsing differentiated thyroid cancer (DTC), the in vivo evaluation of natrium-iodine symporter (NIS) expression is pivotal in the therapeutic planning and is achieved by [131/123I]Iodine whole-body scan. However, these approaches have low sensitivity due to the low sensitivity due to the low resolution of SPECT. [18F]Tetrafluoroborate (TFB) has been proposed as a viable alternative, which could outperform [131/123I]Iodine scans owing to the superior PET resolution.
View Article and Find Full Text PDFUnusual presentation of esophageal tuberculosis: a case study.
BMC Infect Dis
January 2025
Department of Radiation Oncology, Cancer Treatment Center, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Haikou, 570311, China.
Background: Esophageal ulcers can arise not only from malignant lesions but also from benign diseases, such as tuberculosis. These ulcers may mimic the radiological features of esophageal malignancy or tuberculosis on PET/CT, leading to diagnostic challenges.
Case Presentation: A 59-year-old woman was admitted to our hospital with a month-long history of progressive painful swallowing, fatigue, and loss of appetite.
Synchronous primary tumors amd distant metastasis detected on F-FDG PET in patients with head and neck carcinoma.
Asia Ocean J Nucl Med Biol
January 2025
Department of Nuclear medicine, Dr Rajendra Prasad Government medical college,Tanda Kangra Himachal Pradesh, India.
Article Synopsis
- The study focuses on the effectiveness of F-FDG PET/CT in identifying distant metastasis and synchronous tumors in newly diagnosed head and neck cancer patients in North India.
- A total of 281 patients were analyzed, revealing that 11.7% had distant metastases, primarily found in the lungs and bones, while 7% had synchronous malignancies, with lung cancer being the most common.
- These results support the use of whole body F-FDG PET/CT for initial staging as it significantly impacts patient management by detecting additional malignancies early on.
Introduction Tumor staging is essential for determining treatment strategies and predicting prognosis in cancer patients. Accurate imaging techniques are critical for staging, metastasis screening, treatment response assessment, and recurrence detection. Objective In this prospective study, we aimed to compare the sensitivity of whole-body diffusion-weighted imaging (WB-DWI) with positron emission tomography/computed tomography (PET/CT) in detecting metastases.
View Article and Find Full Text PDFThe Role of 11C-Methionine PET Imaging for the Evaluation of Lymphomas: A Systematic Review.
Hematol Rep
November 2024
Nuclear Medicine, Università Degli Studi di Brescia and ASST Spedali Civili di Brescia, 25123 Brescia, Italy.
: In the last years, different evidence has underlined a possible role for [11C]-methionine ([11C]MET) positron emission tomography (PET) imaging for the evaluation of lymphomas. The aim of this paper was, therefore, to review the available scientific literature focusing on this topic. : A wide literature search of the PubMed/MEDLINE, Scopus and Cochrane Library databases was conducted in order to find relevant published articles investigating the role of [11C]MET in the assessment of lymphomas.
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