Nowadays various information documents on toxicity and danger of chemical substances exist, i. e., toxicologic certificates, data profiles, trade certificates, etc. An attempt has been made to analyze 15 available data lists used in various countries for the description of noxious and hazardous characteristics of chemicals. The indices on toxicity and danger of chemicals enumerated in the lists are grouped by 9 main categories. The degree of detailed description of the data presented is determined by the aim of the document. The results thus obtained can be used in the further work aimed at the improvement and unification of the forms providing the data on toxicity and danger of the chemicals.
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Curr Pharm Biotechnol
January 2025
School of Physiotherapy and Rehabilitation, Jamia Hamdard University, India.
Cosmeceutical products such as skin-lightening agents have been used globally to enhance skin tone and obtain a magnificent outward appearance. The pigment known as melanin, produced by melanocytes, imparts skin color. The Cosmetic Europe survey testifies that most people believe that cosmetics enhance one's quality of life.
View Article and Find Full Text PDFAnn Cardiol Angeiol (Paris)
January 2025
Laboratoire centrale de l'établissement hospitalier Didouche Mourad, Constantine, Algérie; Université constantine 3, faculté de médecine, Algérie. Electronic address:
Introduction: The use of medicinal plants in Algeria is an ancestral practice that remains relevant today. The population relies on plants to treat various diseases and everyday ailments, which can be dangerous, especially when taking medication [1,2]. The interaction between plants and medication can lead to a modification of the plasma concentrations of the latter, which can impact its therapeutic effectiveness and be responsible for toxicity or therapeutic failure [1,2].
View Article and Find Full Text PDFJ Environ Sci Health A Tox Hazard Subst Environ Eng
January 2025
Department of Virus Reproduction of Danylo Zabolotny Institute of Microbiology and Virology, NAS of Ukraine, Kyiv, Ukraine.
The influx of insufficiently purified or untreated domestic wastewater into aquatic ecosystems raises the question of the production of environmentally friendly detergents. The purpose of this work was to investigate the toxicity of phosphonate-containing and phosphate-free dishwashing detergents for dishwashers according to the phytotest with a garden cress ( L.).
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Pneumology, Oncology and Allergology, Medical University of Lublin, Jaczewskiego 8, 20-090 Lublin, Poland.
Doxorubicin (DOX) has been widely used as a cytotoxic chemotherapeutic. However, DOX has a number of side effects, such as myelotoxicity or gonadotoxicity, the most dangerous of which is cardiotoxicity. Cardiotoxicity can manifest as cardiac arrhythmias, myocarditis, and pericarditis; life-threatening late cardiotoxicity can result in heart failure months or years after the completion of chemotherapy.
View Article and Find Full Text PDFAntioxidants (Basel)
December 2024
Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre "Kurchatov Institute", 188300 Gatchina, Russia.
Viral infections and many other dangerous diseases are accompanied by the development of oxidative stress, which is a consequence of an increase in the level of the reactive oxygen species (ROS). In this regard, the search for effective antioxidants remains highly relevant. We tested fullerenol C(OH) in the context of the connection between its self-assembly in aqueous solutions and cell culture media, antiradical activity, UV cytoprotective action, and antiviral activity against international reference strains of influenza virus A(H1N1)pdm09, A(H3N2), and B subtypes in vitro on the MDCK cell line.
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