The different factors involved in the growth process of complex networks imprint valuable information in their observable topologies. How to exploit this information to accurately predict structural network changes is the subject of active research. A recent model of network growth sustains that the emergence of properties common to most complex systems is the result of certain trade-offs between node birth-time and similarity. This model has a geometric interpretation in hyperbolic space, where distances between nodes abstract this optimisation process. Current methods for network hyperbolic embedding search for node coordinates that maximise the likelihood that the network was produced by the afore-mentioned model. Here, a different strategy is followed in the form of the Laplacian-based Network Embedding, a simple yet accurate, efficient and data driven manifold learning approach, which allows for the quick geometric analysis of big networks. Comparisons against existing embedding and prediction techniques highlight its applicability to network evolution and link prediction.
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http://dx.doi.org/10.1038/srep30108 | DOI Listing |
Anim Cells Syst (Seoul)
January 2025
Department of Genome Medicine and Science, Gachon University College of Medicine, Incheon, Republic of Korea.
Dynamic modeling of cellular states has emerged as a pivotal approach for understanding complex biological processes such as cell differentiation, disease progression, and tissue development. This review provides a comprehensive overview of current approaches for modeling cellular state dynamics, focusing on techniques ranging from dynamic or static biomolecular network models to deep learning models. We highlight how these approaches integrated with various omics data such as transcriptomics, and single-cell RNA sequencing could be used to capture and predict cellular behavior and transitions.
View Article and Find Full Text PDFJ Soc Cardiovasc Angiogr Interv
December 2024
Division of Cardiovascular Medicine, Virginia Commonwealth University, Richmond, Virginia.
Background: Routine preprocedural fasting before cardiac catheterization remains common practice, despite a lack of robust evidence to support this practice. We investigated the impact of a liberal nonfasting strategy vs a standardized nil per os (NPO) regimen prior to cardiac catheterization.
Methods: Adult inpatients undergoing elective or urgent cardiac catheterization were randomized (1:1 ratio) to either NPO past midnight or ad libitum intake of liquids and solids (without dietary constraints) until immediately prior to the procedure.
Math Biosci Eng
December 2024
School of Information Engineering, Nantong Institute of Technology, Nantong 226002, Jiangsu, China.
As an essential component of mechanical systems, bearing fault diagnosis is crucial to ensure the safe operation of the equipment. However, vibration data from bearings often exhibit non-stationary and nonlinear features, which complicates fault diagnosis. To address this challenge, this paper introduces a novel multi-scale time-frequency and statistical features fusion model (MTSF-FM).
View Article and Find Full Text PDFCurr Med Imaging
January 2025
School of Life Sciences, Tiangong University, Tianjin 300387, China.
Objective: The objective of this research is to enhance pneumonia detection in chest X-rays by leveraging a novel hybrid deep learning model that combines Convolutional Neural Networks (CNNs) with modified Swin Transformer blocks. This study aims to significantly improve diagnostic accuracy, reduce misclassifications, and provide a robust, deployable solution for underdeveloped regions where access to conventional diagnostics and treatment is limited.
Methods: The study developed a hybrid model architecture integrating CNNs with modified Swin Transformer blocks to work seamlessly within the same model.
Adv Sci (Weinh)
January 2025
Department of Orthopaedics Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, China.
Osteointegration, the effective coupling between an implant and bone tissue, is a highly intricate biological process. The initial stages of bone-related immunomodulation and cellular colonization play crucial roles, but have received limited attention. Herein, a novel supramolecular co-assembled coating of strontium (Sr)-doped metal polyphenol networks (MPN) modified with c(RGDfc) is developed and well-characterized, for eliciting an early immunomodulation and cellular colonization.
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