[Prediction of the efficiency of endoscopic lung volume reduction by valves in severe emphysema].

Rev Mal Respir

Clinique universitaire de pneumologie, pôle thorax et vaisseaux, CHU de Grenoble, CS10217, 38043 Grenoble cedex 9, France; Université Grenoble Alpes, 38000 Grenoble, France.

Published: November 2016

Introduction: In severe emphysema, endoscopic lung volume reduction with valves is an alternative to surgery with less morbidity and mortality. In 2015, selection of patients who will respond to this technique is based on emphysema heterogeneity, a complete fissure visible on the CT-scan and absence of collateral ventilation between lobes. Our case report highlights that individualized prediction is possible.

Case Report: A 58-year-old woman had severe, disabling pulmonary emphysema. A high resolution thoracic computed tomography scan showed that the emphysema was heterogeneous, predominantly in the upper lobes, integrity of the left greater fissure and no collateral ventilation with the left lower lobe. A valve was inserted in the left upper lobe bronchus. At one year, clinical and functional benefits were significant with complete atelectasis of the treated lobe.

Conclusion: The success of endoscopic lung volume reduction with a valve can be predicted, an example of personalized medicine.

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Source
http://dx.doi.org/10.1016/j.rmr.2016.02.011DOI Listing

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