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The role of torso stiffness and prediction in the biomechanics of anxiety: a narrative review.
Front Sports Act Living
November 2024
Department of Medicine, Advocate Lutheran General Hospital, Park Ridge, IL, United States.
Article Synopsis
- Anxiety has physical symptoms like palpitations and dizziness, which can lead to severe cardiac events like Takotsubo cardiomyopathy, particularly when coupled with torso stiffness from stress.
- Studying the biomechanics of torso stiffness can help understand how anxiety impacts circulation, as increased stiffness limits venous return and decreases cardiac output.
- Engaging in playful aerobic activities and practicing proper breathing may alleviate anxiety by reducing torso stiffness and improving overall circulation, thus protecting the cardiopulmonary system.
PRKAG2 syndrome, a rare hypertrophic cardiomyopathy: a Brazilian long-term follow-up with extracardiac disorders.
Einstein (Sao Paulo)
July 2024
Medical Science Department, School of Medicine, University of Girona, Girona, Spain.
Article Synopsis
- The study focused on long-term outcomes of PRKAG2 syndrome, a rare genetic disorder that can cause serious heart problems and arrhythmias.
- A cohort of 66 individuals was analyzed, revealing that those with the p.K290I gene mutation faced a high rate of severe health issues, including cardiac events and complications during childbirth.
- Findings emphasize the importance of early diagnosis and intervention to improve patient outcomes, while also suggesting a need for further research into related neurological and pregnancy complications.
Factors associated with initiation of pharmacological therapy and treatment changes in postural orthostatic tachycardia syndrome.
Front Neurol
June 2024
Cleveland Clinic Lerner College of Medicine, Cleveland, OH, United States.
Purpose: Postural Orthostatic Tachycardia Syndrome (POTS) is a heterogenous disorder of the autonomic nervous system that is often disabling. There are no FDA-approved therapies for the treatment of this condition. While some patients recover with baseline non-pharmacological intervention, others require repeated trials of off-label pharmacological therapies.
View Article and Find Full Text PDFIllness presentation and quality of life in myalgic encephalomyelitis/chronic fatigue syndrome and post COVID-19 condition: a pilot Australian cross-sectional study.
Qual Life Res
September 2024
National Centre for Neuroimmunology and Emerging Diseases, Griffith University, Gold Coast, QLD, 4222, Australia.
Purpose: Post COVID-19 Condition (PCC), being persistent COVID-19 symptoms, is reminiscent of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)-a chronic multi-systemic illness characterised by neurocognitive, autonomic, endocrinological and immunological disturbances. This novel cross-sectional investigation aims to: (1) compare symptoms among people with ME/CFS (pwME/CFS) and people with PCC (pwPCC) to inform developing PCC diagnostic criteria; and (2) compare health outcomes between patients and people without acute or chronic illness (controls) to highlight the illness burdens of ME/CFS and PCC.
Methods: Sociodemographic and health outcome data were collected from n = 61 pwME/CFS, n = 31 pwPCC and n = 54 controls via validated, self-administered questionnaires, including the 36-Item Short-Form Health Survey version 2 (SF-36v2) and World Health Organization Disability Assessment Schedule version 2.
Role of the vessel morphology on the lenticulostriate arteries hemodynamics during atrial fibrillation: A CFD-based multivariate regression analysis.
Comput Methods Programs Biomed
September 2024
Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy.
Article Synopsis
- Atrial fibrillation (AF) is linked to an increased risk of vascular dementia and cognitive impairment due to changes in deep cerebral blood flow, with lenticulostriate arteries (LSAs) being particularly affected.
- The study used computational fluid dynamics (CFD) and high-resolution MRI to analyze the LSA's shape and its influence on blood flow during AF, identifying key features like MCA size and bifurcation angles.
- Findings suggest that LSAs with larger angles and smaller MCA sizes may be more susceptible to vascular damage caused by AF, highlighting the importance of LSA morphology in cerebral hemodynamics.
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