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An international survey of patient blood management practices.
Transfusion
January 2025
Association for the Advancement of Blood and Biotherapies, Bethesda, Maryland, USA.
Background: The Association for the Advancement of Blood and Biotherapies (AABB) conducted a global survey of patient blood management (PBM) practices. It determined changes in PBM practices since the last survey.
Study Design And Methods: A working group of AABB's PBM Subsection and AABB staff designed the survey using the Qualtrics™ platform.
The Application of Olive-Derived Polyphenols on Exercise-Induced Inflammation: A Scoping Review.
Nutrients
January 2025
Cambridge Centre for Sport and Exercise Sciences (CCSES), Faculty of Science and Engineering, Anglia Ruskin University, Cambridge CB1 1PT, UK.
Background/objectives: There is current scientific interest pertaining to the therapeutic effects of olive-derived polyphenols (ODPs), in particular their associated anti-inflammatory properties, following the wealth of research surrounding the physiological impact of the Mediterranean Diet (MD). Despite this association, the majority of the current literature investigates ODPs in conjunction with metabolic diseases. There is limited research focusing on ODPs and acute inflammation following exercise, regardless of the knowledge surrounding the elevated inflammatory response during this time.
View Article and Find Full Text PDFBackground: Neuroendocrine carcinomas (NECs) are treated with a frontline platinum-etoposide combination with no standard second-line therapies. We explored a novel combination of nanoliposomal irinotecan (Nal-IRI), 5-fluorouracil (5-FU), and leucovorin (LV) in advanced refractory NECs and investigated the impact of UGT1A1*28 polymorphism on treatment outcomes and toxicity.
Methods: We conducted an open-label, single-arm, multi-center Phase 2 trial in advanced NEC patients of gastroenteropancreatic (GEP) or unknown origin with progression or intolerance to first-line therapy.
Wish-Granting Interventions Promote Positive Emotions in Both the Short and Long Term in Children with Critical Illnesses and Their Families.
Children (Basel)
December 2024
Close of Life, Graaf Zeppelinlaan 23, 1185 HC Amstelveen, The Netherlands.
Background: Wish-granting interventions are recognized as positive experiences for children with critical illness and their families. While the positive effects have been shown in the immediate and short term, data on their long-term effects are lacking.
Objectives: To evaluate the effects of wish-granting interventions on children and parents during and post intervention-both in the weeks after, and up to 5 years after-and to examine any differences between these two groups.
Assessment of IL-6 Pathway Inhibition in Gastrointestinal Behçet's Disease from Immunological and Clinical Perspectives.
Biomedicines
January 2025
Department of Gastroenterology and Hepatology, Kyorin University School of Medicine, Tokyo 181-0004, Japan.
Behçet's disease is an autoinflammatory disorder characterized by relapsing and remitting vasculitis that can manifest in various forms, including gastrointestinal Behçet's disease (GIBD). Its complications (e.g.
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