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Conventional versus daylight photodynamic therapy for recalcitrant hand warts: Efficacy, safety and recurrence.
Photodiagnosis Photodyn Ther
December 2024
Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina 98125, Italy. Electronic address:
Article Synopsis
- Acral warts, common on hands and feet, can be treated with conventional photodynamic therapy (C-PDT), which has been effective and safe for both adults and children, but the efficacy of daylight photodynamic therapy (DL-PDT) is still unclear.
- A study involving 68 patients aimed to compare the short- and long-term effects of C-PDT and DL-PDT using 10% aminolevulinic acid (ALA) on hand warts, with evaluations of responses occurring at 3 months and 1 year post-treatment.
- Results showed that both treatments were generally effective and well-tolerated, with a majority of patients experiencing excellent responses; however, a notable percentage had warts relapse a year later
Dermatoscopy of subungual digital fibromyxoma (superficial acral fibromyxoma).
JAAD Case Rep
March 2023
Dermatopathology private practice, San Salvador, El Salvador.
Oral verruciform hyperkeratotic lesions indicating the presence of plantar or palmoplantar keratodermas.
Oral Surg Oral Med Oral Pathol Oral Radiol
October 2022
Division of Oral and Maxillofacial Pathology, School of Dentistry, University of Minnesota, Minneapolis, MN, USA; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN, USA; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN, USA.
Article Synopsis
- The study examines oral verruciform hyperkeratotic lesions (OVHLs) that appear in the gingiva and palate, primarily in the context of proliferative verrucous leukoplakia (PVL), while also exploring their association with skin conditions like plantar keratodermas (PK) and palmoplantar keratodermas (PPKs).
- Five patients aged 18 to 64, initially diagnosed with PVL due to their oral leukoplakias, were found to have histopathological features linking their oral lesions to PK or PPKs after biopsies were performed.
- The researchers concluded that these oral lesions have distinct histopathological characteristics and a slow biological progression, suggesting that they
Dermatophytomas: Clinical Overview and Treatment.
J Fungi (Basel)
July 2022
Mediprobe Research Inc., 645 Windermere Road, London, ON N5X 2P1, Canada.
Dermatophytomas are characterized as a hyperkeratotic fungal mass in the subungual space, showing as dense white or yellow, typically in longitudinal streaks or patches. Masses can be visualized by traditional microscopy or histology. Newer technologies such as dermoscopy and optical coherence tomography also provide visual features for dermatophytoma diagnosis.
View Article and Find Full Text PDFAcquired digital fibrokeratoma presenting as a painless nodule on the right fifth fingernail.
Cutis
June 2019
Department of Dermatology, Weill Cornell Medicine, New York, New York, USA.
Article Synopsis
- A 53-year-old woman had a painless nodule on her right pinky nail that grew over the past year, leading to a biopsy.
- The biopsy revealed features consistent with an acquired digital fibrokeratoma (ADF), which is characterized by specific changes in the skin layers, and there was no recurrence after 4 months post-surgery.
- The case emphasizes the importance of recognizing ADF among other possible nail tumors, as well as understanding its clinical and histopathological features despite the absence of known risk factors.
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