Background And Aim: Large skull base defects are extremely difficult to treat and have a severe impact on patients' physical appearance and functional aspects. These extensive defect zones are mainly caused by trauma, surgical interventions, or wide tumor excision. High-level microsurgical techniques are necessary to provide sufficient treatment. The aim of this study is to describe successful reconstructive strategies for surgical treatment.
Methods: Nine patients with skull base defects were treated in our department from 2008 to 2014 (n = 9). Plastic surgical reconstruction was performed with latissimus dorsi (LD;) (n = 4), LD-scapula flaps (n = 2), vertical rectus abdominis myocutaneous (VRAM) flaps (n = 2), and a greater omentum flap (n = 1). The mean follow-up period was 2.3 ± 2.2 years (0.5-4.5 years). Oncologic diseases (8 patients) and iatrogenic damage (1 patient) caused the massive skull base defects.
Results: In all cases, we achieved the final surgical treatment of large skull base defects by free flaps with permanent wound closure. The mean operating time was 5:53 h (range 4:45-7:52 h). The primary outcome measures were survival and sufficient defect coverage. Flap survival rate was 100%, and none of the patients deceased during the follow-up period. Furthermore, we demonstrated the surgical key points of LD-scapula flap closure in detail.
Conclusion: Plastic surgical defect coverage by well-perfused tissue flaps of large skull base defects provides an efficient and effective treatment option. Complex skin, soft tissue, and dural defects can be successfully covered with these preformed free flaps. The choice of flap is based on the individual case.
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http://dx.doi.org/10.1016/j.bjps.2016.06.008 | DOI Listing |
Cancers (Basel)
December 2024
Department of Neurosurgery, Institute of Medicine, University of Tsukuba, Tsukuba 305-8575, Japan.
Skull base tumors such as meningiomas and schwannomas are often pathologically benign. However, surgery for these tumors poses significant challenges because of their proximity to critical structures such as the brainstem, cerebral arteries, veins, and cranial nerves. These structures are compressed or encased by the tumor as they grow, increasing the risk of unintended injury to these structures, which can potentially lead to severe neurological deficits.
View Article and Find Full Text PDFCancers (Basel)
December 2024
Department of Neurological Surgery, Houston Methodist Neurological Institute, Houston Methodist Hospital, Houston, TX 77030, USA.
Radiation has been used to treat meningiomas since the mid-1970s. Traditionally, radiation was reserved for patients unfit for major surgery or those with surgically inaccessible tumors. With an increased quantity and quality of imaging, and an aging population, there has been a rise in incidentally diagnosed meningiomas with smaller tumors at diagnosis time.
View Article and Find Full Text PDFDiagnostics (Basel)
December 2024
Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Goudi, 11 527 Athens, Greece.
: The caroticoclinoid bar (CCB) or caroticoclinoid foramen (CCF) represents a well-described ossified variant of the skull base. It corresponds to an osseous bridge (resulting after homonymous ligament ossification) between the anterior and middle clinoid processes (ACPs and MCPs) surrounding the internal carotid artery (ICA)'s cavernous segment. Although extensive research has been performed on this clinically significant entity, only a few studies have been conducted on its effect on the ICA.
View Article and Find Full Text PDFJ Neurosurg
January 2025
Departments of1Neurological Surgery.
Objective: Tumor consistency, or fibrosity, affects the ability to optimally resect meningiomas, especially with recent trends evolving toward minimally invasive approaches. The authors' team previously validated a practical 5-point scale for intraoperative grading of meningioma consistency. The impact of meningioma consistency on surgical management and outcomes, however, has yet to be explored.
View Article and Find Full Text PDFNeurosurg Rev
January 2025
Iranian Center of Neurological Research, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Stereotactic radiosurgery (SRS) and radiotherapy (SRT) have gained prominence as both adjuvant and primary treatment options for patients with skull base tumors that are either inoperable or present as residual or recurrent lesions post-surgery. The object of the current study is to evaluate the safety and efficacy of robotic-assisted SRS and SRT across various skull base pathologies. The study was conducted under PRISMA guidelines and involved a comprehensive evaluation of databases, including PubMed, Scopus, Embase, Web-of-Science, and the Cochrane Library.
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