Biological Characteristics of Captive Chinese Wuzhishan Minipigs (Sus scrofa).

Int Sch Res Notices

Guangdong Dahuanong Animal Health Products Stock Co., Ltd., Xinxing 527439, China.

Published: July 2016

In order to meet the demands of experimental minipigs for biomedical researches, we have aimed at cultivating grazing Chinese Wuzhishan (WZS) minipigs and trying to make them useful and affordable since the 1990s. After more than ten years of captive cultivation following sound management practices and a rigorous selection program for fertility and litter size, we established an outbred WZS minipigs colony with a core group (14 males and 30 females) and an expanding group (20 males and 40 females). In 2010-2013 periods, extensive background data of this colony were recorded and analyzed. This paper was written to provide pertinent information about outbred WZS minipigs for producers, users, and others concerned with WZS minipigs. It contains physical characteristics, growth performance, productive performance, hematology and blood biochemistry, microsatellite analysis, organ coefficients, and carcass properties. Results show that WZS minipigs have characteristics of small body size, slow growth rate, long life cycle, high reproductive rate, and maintaining original genetic diversity. All data present that outbred WZS minipigs are suitable laboratory animal and model animal.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4897273PMC
http://dx.doi.org/10.1155/2014/761257DOI Listing

Publication Analysis

Top Keywords

wzs minipigs
24
outbred wzs
12
chinese wuzhishan
8
minipigs
8
group males
8
males females
8
wzs
6
biological characteristics
4
characteristics captive
4
captive chinese
4

Similar Publications

Wuzhishan miniature pig-derived intestinal 2D monolayer organoids to investigate the enteric coronavirus infection.

Front Vet Sci

September 2024

Key Laboratory of Tropical Animal Breeding and Disease Research, Institute of Animal Husbandry and Veterinary Medicine, Hainan Academy of Agricultural Sciences, Haikou, China.

Article Synopsis
  • - The study developed intestinal organoids from Wuzhishan miniature pigs (WZS pigs), providing a new model for researching intestinal health and disease.
  • - Researchers created 3D organoids and monolayers, which were tested for their vulnerability to the transmissible gastroenteritis virus (TGEV).
  • - RNA-seq analysis showed that TGEV infection triggered immune responses, highlighting potential risks of swine enteric coronavirus transmission in WZS pigs and supporting their use as laboratory models.
View Article and Find Full Text PDF

Wuzhishan (WZS) pigs, which are minipigs native to Hainan Province in China, are characterized by strong resistance to extreme hot temperatures and humidity. The relationship between their immune response and growth still needs to be clarified. In this study, we used whole genome sequencing (WGS) to detect variations within 37 WZS pigs, 32 Large White (LW) pigs, and 22 Xiangxi black (XXB) pigs, and ~2.

View Article and Find Full Text PDF

[Protective effect and mechanism of mild hypothermia on liver injury after cardiopulmonary resuscitation in pigs].

Zhonghua Yi Xue Za Zhi

September 2020

Department of Gastroenterology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.

To investigate the effect of mild hypothermia therapy on liver after cardiopulmonary resuscitation. Thirty-three inbred Chinese Wuzhishan (WZS) minipigs, weighted (28±2) kg, were used to establish a ventricular fibrillation model. And 30 animals survived after cardiopulmonary resuscitation reached basic life support.

View Article and Find Full Text PDF

Here, we performed whole-genome bisulfite sequencing of longissimus dorsi muscle from Landrace and Wuzhishan (WZS) miniature pigs during 18, 21, and 28 d postcoitum. It was uncovered that in regulatory regions only around transcription start sites (TSSs), gene expression and methylation showed negative correlation, whereas in gene bodies, positive correlation occurred. Furthermore, earlier myogenic gene demethylation around TSSs and earlier hypermethylation of myogenic genes in gene bodies were considered to trigger their earlier expression in miniature pigs.

View Article and Find Full Text PDF

To isolate bone marrow mesenchymal stem cells (BM-MSCs) and establish the model of chronic kidney disease (CKD) of Wuzhishan (WZS) mini-pig, and to study the repairment effect of BM-MSCs on CKD-induced renal fibrosis in vitro.
 Methods: Density gradient method was used to isolate and culture BM-MSCs. The cells were verified by morphology, phenotype, differentiation and so on.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!