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http://dx.doi.org/10.1083/jcb.20151001207062016c | DOI Listing |
ACS Appl Mater Interfaces
December 2022
Department of Chemical Engineering, Columbia Electrochemical Engineering Center, Lenfest Center for Sustainable Energy, Columbia University in the City of New York, New York, New York10027, United States.
Encapsulation of electrocatalysts and photocatalysts with semipermeable nanoscopic oxide overlayers that exhibit selective transport properties is an attractive approach to achieve high redox selectivity. However, defects within the overlayers─such as pinholes, cracks, or particle inclusions─may facilitate local high rates of parasitic reactions by creating pathways for facile transport of undesired reactants to exposed active sites. Scanning electrochemical microscopy (SECM) is an attractive method to determine the influence of defects on macroscopic performance metrics thanks to its ability to measure the relative rates of competing electrochemical reactions with high spatial resolution over the electrode.
View Article and Find Full Text PDFAdv Mater
September 2023
Sandia National Laboratories, Livermore, CA, 94550, USA.
Emerging concepts for neuromorphic computing, bioelectronics, and brain-computer interfacing inspire new research avenues aimed at understanding the relationship between oxidation state and conductivity in unexplored materials. This report expands the materials playground for neuromorphic devices to include a mixed valence inorganic 3D coordination framework, a ruthenium Prussian blue analog (RuPBA), for flexible and biocompatible artificial synapses that reversibly switch conductance by more than four orders of magnitude based on electrochemically tunable oxidation state. The electrochemically tunable degree of mixed valency and electronic coupling between N-coordinated Ru sites controls the carrier concentration and mobility, as supported by density functional theory computations and application of electron transfer theory to in situ spectroscopy of intervalence charge transfer.
View Article and Find Full Text PDFSci Rep
November 2022
Electronics and Communication Engineering Discipline, Khulna University, Khulna, 9208, Bangladesh.
In recent years, the omnipresence of cardiac problems has been recognized as an epidemic. With the correct and quick diagnosis, both mortality and morbidity from cardiac disorders can be dramatically reduced. However, frequent medical check-ups are pricey and out of reach for a large number of people, particularly those living in low-income areas.
View Article and Find Full Text PDFFront Immunol
October 2022
Department of Immunology, Ophthalmology and Otorhinolaryngology, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain.
Activation of the integrin phagocytic receptors CR3 (αβ, CD11b/CD18) and CR4 (αβ, CD11c/CD18) requires Rap1 activation and RIAM function. RIAM controls integrin activation by recruiting Talin to β subunits, enabling the Talin-Vinculin interaction, which in term bridges integrins to the actin-cytoskeleton. RIAM also recruits VASP to phagocytic cups and facilitates VASP phosphorylation and function promoting particle internalization.
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