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PET FDG CT is useful for giant-cell arteritis with isolated cough.
Rheumatol Int
December 2023
Service de Medicine Interne and Inflammation-Immunopathology-Biotherapy Department (DMU i2), Sorbonne Université, AP-HP, Hôpital Saint-Antoine, 75012, Paris, France.
Giant cell arteritis (GCA) is a chronic vasculitis of large- and medium-sized vessels. The most frequent symptoms are temporal headaches, scalp tenderness, jaw claudication and polymyalgia rheumatica in 35% of patients. Atypical presentation with dry cough is very rare and could be isolated making the diagnosis difficult.
View Article and Find Full Text PDFA case of glial fibrillary acidotic protein (GFAP) meningoencephalitis with rheumatoid arthritis.
Clin Case Rep
March 2023
Functional Neurosurgery Research Center, Shohada Tajrish Neurosurgical Center of Excellence Shahid Beheshti University of medical Sciences Tehran Iran.
Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is an inflammatory disease of the central nervous system (CNS), which affects various regions in the CNS, presenting by variable clinical manifestations. Meningoencephalitis is the most common clinical presentation and association with autoimmune disorders has been reported in about 20% of these patients. Diagnosis is confirmed by the presence of CSF or serum immunoglobulin-G (IgG) against GFAP.
View Article and Find Full Text PDFTolosa-Hunt syndrome presenting with features of a trigeminal autonomic cephalalgias and pituitary enlargement.
BMJ Case Rep
March 2022
Neurology, Leeds Teaching Hospitals NHS Trust, Leeds, UK.
Tolosa-Hunt syndrome is understood as a steroid-responsive, relapsing-remitting, unilateral headache disorder associated with ipsilateral cranial neuropathies, of a probable granulomatous aetiology. The diagnosis is made clinically from the history and examination, supported by appropriate imaging. Here the authors report a case of Tolosa-Hunt syndrome with a headache phenotype mimicking a trigeminal autonomic cephalalgias (hemicrania continua), and serial MRI studies showing a stable enlarged pituitary.
View Article and Find Full Text PDFAnti-GFAP Antibody-Associated Hypertrophic Pachymeningitis.
Neuropediatrics
April 2022
Department of Neurology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders Chongqing, People's Republic of China.
Background: Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is an inflammatory central nervous system (CNS) disorder that usually presents as steroid responsive encephalitis, meningitis, myelitis, or meningoencephalomyelitis. Hypertrophic pachymeningitis (HP) is an uncommon disorder that causes a localized or diffuse thickening of the dura mater. Depending on the etiology, HP can be idiopathic or secondary to a wide variety of other diseases.
View Article and Find Full Text PDFSteroid-Responsive Gradenigo's Syndrome Mimicking Subdural Hematoma.
Cureus
November 2021
Department of Neurology, Tri-Service General Hospital, National Defense Medical Center, Taipei, TWN.
Gradenigo's syndrome (GS) is featured by a clinical triad of otorrhea, retro-orbital pain, and a sixth nerve palsy. Clinical examination is crucial prior to considering neuroimaging. The majority of cases are secondary to infection thus requiring long-term broad-spectrum antibiotics; severe cases also require surgical intervention for risk of intracranial abscess or even death.
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