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First isolation of Candida wangnamkhiaoensis from the blood of immunocompromised paediatric patient. | LitMetric

AI Article Synopsis

  • Candida wangnamkhiaoensis is a newly identified species within the Hyphopichia clade, previously not found in clinical settings.
  • This report marks the first association of C. wangnamkhiaoensis with fungaemia in an immunocompromised pediatric patient, identified as strain UZ1679/14 through PCR-sequencing methods.
  • The isolate demonstrated sensitivity to multiple antifungal medications, and the patient showed clinical improvement after treatment with caspofungin.

Article Abstract

Candida wangnamkhiaoensis is a species clustered under the Hyphopichia clade has not ever been isolated from any clinical specimens. To the best of our knowledge, this is the first report of C. wangnamkhiaoensis associated with fungaemia in immunocompromised paediatric patient. The isolate was assigned a strain name as UZ1679/14, in which the identification was confirmed by a polymerase chain reaction-sequencing of the internal transcribed spacer (ITS) and large subunit (LSU) regions of the rRNA gene. Antifungal susceptibility pattern showed that the isolate was sensitive to anidulafungin, caspofungin, fluconazole and voriconazole. The patient clinically improved after the antifungal treatment with caspofungin.

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Source
http://dx.doi.org/10.1111/myc.12509DOI Listing

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