AI Article Synopsis
- A matched and mixed capping SAR study was performed on tetracyclic indole compounds targeting HCV NS5A inhibitors.
- The study aimed to explore how changes to this chemical structure affect their effectiveness against the hepatitis C virus.
- Results from the study provide insights into how modifications can influence the virus's resistance to these inhibitors.
Article Abstract
A matched and mixed capping SAR study was conducted on the tetracyclic indole class of HCV NS5A inhibitors to examine the influence of modifications of this region on the overall HCV virologic resistance profiles.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.bmcl.2016.06.063 | DOI Listing |
Publication Analysis
Top Keywords
matched mixed
8
tetracyclic indole
8
indole class
8
class hcv
8
hcv ns5a
8
ns5a inhibitors
8
mixed cap
4
cap derivatives
4
derivatives tetracyclic
4
inhibitors matched
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!