Identification and derivatization of selected cathinones by spectroscopic studies.

Forensic Sci Int

Institute of Chemistry, University of Silesia, ul. Szkolna 9, 40007 Katowice, Poland.

Published: September 2016

AI Article Synopsis

  • The study introduces three new hydrochloride salts of cathinones: TH-PVP, 2-MMC, and 4-CMC.
  • Their properties were analyzed using various techniques, including GC-MS, IR, NMR, and X-ray diffraction.
  • NMR spectra provided clear signals for certain groups in the molecules, and methods like thionation and amination were used for identifying specific cathinones.

Article Abstract

In this study we identified three novel hydrochloride salts of cathinones 2-(pyrrolidin-1-yl)-1-(5,6,7,8-tetrahydronaphthalen-2-yl)pentan-1-one (1a) (TH-PVP), 2-(methylamino)-1-(2-methylphenyl)-1-propanone (1b) (2-MMC) and 1-(4-chlorophenyl)-2-(methylamino)propan-1-one (1c) (4-CMC). Their properties have been examined through combinations of GC-MS, IR, NMR, electronic absorption spectroscopy and single crystal X-ray diffraction method. NMR solution spectra showed readily diagnostic H-1 and C-13 signals from methyl, N-methyl and carbonyl groups. Additionally the use of thionation and amination reactions for identification of selected cathinones was presented.

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Source
http://dx.doi.org/10.1016/j.forsciint.2016.06.034DOI Listing

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