Standard treatment for severe Clostridium difficile infection (CDI) is oral vancomycin with metronidazole. After failure of this standard regimen, treatment becomes challenging. A young woman treated for septic shock developed CDI. Standard treatment failed and she was ineligible for fecal transplant. Addition of tigecycline to her regimen resulted in cure.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943546PMC
http://dx.doi.org/10.1093/ofid/ofw094DOI Listing

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