Background: Aural plaques can be found on the inner surfaces of one or both ears of horses. Despite their low malignancy, these lesions can sometimes cause discomfort and sensitivity in horses, and a loss in commercial value due to their aesthetic effect. There has been a study describing the epidemiological features and the clinical prevalence of equine aural plaques in Brazil.
Hypothesis/objectives: To determine the clinical prevalence and selected associated factors of aural plaques.
Animals: In the study, 891 horses were assessed for aural plaques. The sample group had a median age of 5 years and comprised both sexes and various breeds from different regions of Brazil.
Methods: Horses were evaluated by a general observation of the body and a detailed observation of both ears. Data on the management system, characteristics of the lesions, the presence of ticks and ear grooming were collected for 109 clinically affected horses. An assessment of the frequency distribution of the disease and its characteristics was performed. Association tests were conducted to establish the relationships between the variables studied.
Results: In 85% (40 of 47) of farms assessed, at least one horse presented with aural plaques. In 14.8% (132 of 891) of the horses, lesions characteristic of aural plaque were detected. Significant associations between the prevalence of "coalescing" lesions and a "semi-intensive" management system and ear grooming were detected.
Conclusions: The findings confirm the extensive distribution of this disease in Brazil and its association with several management factors.
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http://dx.doi.org/10.1111/vde.12360 | DOI Listing |
Cancer Treat Res Commun
November 2024
Department of Otolaryngology - Head and Neck Surgery, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy; Alma Mater Studiorum - Università di Bologna, Italy. Electronic address:
Objective: To review the published cases of meningioma en plaque of the temporal bone (TB-MEP), to gather evidence on the clinical assessment and management of this rare entity.
Methods: Following PRISMA statement recommendations, 383 abstracts were screened independently by two authors. Inclusion criteria were articles of human patients affected by TB-MEP; English or Italian language; availability of the abstract articles unrelated to TB-MEP, guidelines and systematic reviews were excluded.
Vet Res Commun
November 2024
School of Veterinary Medicine, Universidade Federal de Uberlândia, Av. Mato Grosso n. 3289 - Bloco 2S. Bairro Umuarama. CEP 38405-314, Uberlândia, Minas Gerais, Brazil.
The association between aural plaques, Equus caballus papillomavirus (EcPV), and the different breeds of horses and risk factors is poorly described. The objective of this study was to determine the clinical prevalence of aural plaques in Mangalarga Marchador (MM) and Quarter Horse (QH) horses in Brazil, to evaluate the association of this prevalence with some risk factors, and to detect the presence of EcPV DNA (types 1-10) in aural plaques biopsies. A total of 400 MM and 425 QH horses, were clinically evaluated.
View Article and Find Full Text PDFCureus
July 2024
Pediatric Dentistry, Damascus University, Damascus, SYR.
Background Hearing-impaired children may face challenges in communication, social interaction, academic performance, and emotional well-being, which can have a notable impact on their overall quality of life. Beyond these challenges, oral health can also be significantly impacted. The relationship between hearing impairment and dental diseases is an intriguing and interconnected aspect of overall well-being that merits attention and exploration.
View Article and Find Full Text PDFJ Prev Alzheimers Dis
February 2024
Soeren Mattke, M.D., D.Sc., Director, Center for Improving Chronic Illness Care, Research Professor of Economics, USC Dornsife, 635 Downey Way, #505N, Los Angeles, CA 90089, Mobile: +1 202 468 5797,
Introduction: As treatments for secondary prevention of Alzheimer's disease (AD) are being studied, concerns about their value for money have appeared. We estimate cost-effectiveness of a hypothetical screening and prevention program.
Methods: We use a Markov model to project cost-effectiveness of a treatment that reduces progression to symptomatic AD by 50% with either chronic treatment until progression to mild cognitive impairment or treatment for one year followed by monitoring with AD blood tests and retreatment with one dose in case of amyloid re-accumulation.
Alzheimers Dement
March 2024
Clinical Development, Neuroscience, Novartis Pharma AG, Basel, Switzerland.
Introduction: Alzheimer's Prevention Initiative Generation Study 1 evaluated amyloid beta (Aβ) active immunotherapy (vaccine) CAD106 and BACE-1 inhibitor umibecestat in cognitively unimpaired 60- to 75-year-old participants at genetic risk for Alzheimer's disease (AD). The study was reduced in size and terminated early. Results from the CAD106 cohort are presented.
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