The authors' findings confirm the possibility of such forms. In 16.5% of cases lupus erythematosus transforms from the discoid form and in 6.9% of cases from the disseminated form, immunologically presenting as T- or B-dependent lupus erythematosus. The authors describe immunocorrecting therapy for various forms of the disease, including immunosuppression of T- and B-lymphocytes by the quinoline series drugs or by their combinations with corticosteroids, as well as immunostimulation of T-lymphocytes by the imidazole series drugs or by thymus hormones.

Download full-text PDF

Source

Publication Analysis

Top Keywords

lupus erythematosus
12
series drugs
8
[transitory presystemic
4
presystemic forms
4
forms lupus
4
erythematosus characteristics
4
characteristics immunotherapy]
4
immunotherapy] authors'
4
authors' findings
4
findings confirm
4

Similar Publications

Objective: This study investigates the barriers and facilitators to sustaining a decision aid (DA) tool for patients with systemic lupus erythematosus (SLE) in routine rheumatology outpatient care across the U.S. The DA was initially developed for assisting Patients with SLE in making informed medication choices by providing personalized information on their treatment process.

View Article and Find Full Text PDF

Introduction: Bruton's tyrosine kinase (BTK) is a cytoplasmic signaling protein expressed across a variety of immune cells, terminally differentiated plasma cells, and natural killer cells. Due to the signal potential and targetable nature of BTK, the use of BTK inhibitors (BTKis) has been proposed for the management of several diseases. Currently, the use of BTKis is under investigations for several dermatological conditions such as pemphigus, systemic lupus erythematosus, hidradenitis suppurativa, atopic dermatitis, and chronic spontaneous urticaria (CSU).

View Article and Find Full Text PDF

A scientometric study on research trends and characteristics of discoid lupus erythematosus.

J Dent Sci

January 2025

Department of Oral and Maxillofacial-Head and Neck Oncology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background/purpose: Discoid lupus erythematosus (DLE) serves as an interdisciplinary disease involved in dermatology and stomatology in many cases. The purpose of this study was to analyze the scientometric characteristics and research trends of DLE.

Materials And Methods: All the papers on DLE were comprehensively retrieved from the Scopus database.

View Article and Find Full Text PDF

Big Heart, Small Shoes: Heart Failure in Systemic Lupus Erythematosus, More Than Lupus Cardiac Involvement.

CJC Open

January 2025

Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College; National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology; State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital; Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, China.

View Article and Find Full Text PDF

Ten tips in lupus nephritis management.

Clin Kidney J

January 2025

Division of Nephrology, School of Clinical Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong SAR.

Lupus nephritis is an important cause of severe glomerulonephritis, and a leading cause of kidney failure in young adults. While the disease can lead to rapid destruction of nephrons if untreated, there are effective therapies to reverse the severe acute kidney injury and prevent the lifetime risk of kidney failure. Early diagnosis and timely intervention are therefore of critical importance.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!