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Prognostic value of biomarkers of ischaemia in patients with peripheral arterial disease following endovascular revascularisation.
Vasa
January 2025
Department of Vascular Diseases, University Medical Centre Ljubljana, Slovenia.
Our aim was to evaluate the prognostic value of detectable high-sensitivity cardiac troponin I (hs-cTnI) and ischaemia-modified albumin (IMA) in predicting all-cause death or non-fatal ischaemic events in patients with PAD after endovascular revascularisation of the lower limbs. Patients who underwent successful endovascular revascularisation for chronic limb-threatening ischaemia (CLTI) or disabling intermittent claudication (IC) were prospectively included. Pre-procedural levels of hs-cTnI and IMA were measured, and patients were followed for one year for the occurrence of the composite outcome of all-cause death, non-fatal myocardial infarction, new-onset angina, non-fatal ischaemic stroke, transient ischaemic attack, or progression of PAD.
View Article and Find Full Text PDFPredictive potential of pre-procedural cardiac and inflammatory biomarkers regarding mortality following transcatheter aortic valve implantation: A systematic review and meta-analysis.
Heart Lung
November 2024
Sina Hospital Department of Internal Medicine, Tehran, Iran. Electronic address:
Background: Aortic stenosis (AS) is a common heart valve disease, especially in aging populations. While surgical aortic valve replacement (SAVR) is the standard treatment, many patients are ineligible. Transcatheter aortic valve implantation (TAVI) offers an alternative, especially for high-risk patients, but is not without complications.
View Article and Find Full Text PDFUric Acid to Albumin Ratio as a Predictive Marker for Intracoronary Thrombus Severity in ST-Segment Elevation Myocardial Infarction (STEMI) Patients Undergoing Primary Percutaneous Coronary Intervention (PCI).
Med Sci Monit
October 2024
Department of Cardiology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, Turkey.
BACKGROUND This study assessed the association between a novel inflammatory marker, uric acid (UA)-to-albumin ratio (UAR), and preprocedural intracoronary artery thrombus (ICAT) in ST elevation myocardial infarction (STEMI). MATERIAL AND METHODS A total of 171 STEMI patients treated by primary percutaneous coronary intervention between February and December 2023 were evaluated prospectively in this cross-sectional study. The patients were stratified into 2 groups as low (grades 1 to 3) and high-(ICAT) groups (grades 4 and 5).
View Article and Find Full Text PDFSystemic Effects and Absorption of Subepithelial Dexamethasone Vocal Fold Injections.
Laryngoscope
February 2025
Department of Otolaryngology, Monash Health, Melbourne, Victoria, Australia.
Article Synopsis
- The study aimed to compare the systemic effects of two vocal fold procedures: steroid injections (VFSI) and augmentation (VFA) while assessing how these procedures impact cortisol levels and other health markers over time.
- In a controlled study with 14 patients receiving VFSI and 36 receiving VFA, significant decreases in serum and salivary cortisol levels were observed after the steroid injections, but no significant changes were noted for patients undergoing VFA.
- The results indicate that VFSI leads to temporary suppression of the body’s HPA axis due to systemic absorption of dexamethasone, which normalizes within a few days, while VFA does not significantly affect cortisol levels or other measured health
Utility of pre-procedural [Tc]TcMAA SPECT/CT Multicompartment Dosimetry for Treatment Planning of Y Glass microspheres in patients with Hepatocellular Carcinoma: comparison of anatomic versus [Tc]TcMAA-based Segmentation.
Eur J Nucl Med Mol Imaging
January 2025
Department of Radiology, Northwestern Feinberg School of Medicine, Chicago, IL, USA.
Purpose: Pre-treatment [Tc]TcMAA-based radioembolization treatment planning using multicompartment dosimetry involves the definition of the tumor and normal tissue compartments and calculation of the prescribed absorbed doses. The aim was to compare the real-world utility of anatomic and [Tc]TcMAA-based segmentation of tumor and normal tissue compartments.
Materials And Methods: Included patients had HCC treated by glass [Y]yttrium microspheres, ≥ 1 tumor, ≥ 3 cm diameter and [Tc]TcMAA SPECT/CT imaging before treatment.
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